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MYCTU:PKS1
Contents
| Species (Taxon ID) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). (83332) | |
| Gene Name(s) | pks1 | |
| Protein Name(s) | Putative inactive phenolphthiocerol synthesis polyketide synthase type I Pks1 | |
| External Links | ||
| UniProt | P96285 | |
| EMBL | AL123456 | |
| RefSeq | NP_217462.1 YP_006516399.1 | |
| ProteinModelPortal | P96285 | |
| STRING | 83332.Rv2946c | |
| PRIDE | P96285 | |
| EnsemblBacteria | CCP45750 | |
| GeneID | 13317740 888122 | |
| KEGG | mtu:Rv2946c mtv:RVBD_2946c | |
| PATRIC | 18155143 | |
| TubercuList | Rv2946c | |
| eggNOG | COG3321 | |
| HOGENOM | HOG000046292 | |
| InParanoid | P96285 | |
| KO | K12430 | |
| OMA | NEIRICE | |
| OrthoDB | EOG6QP0WP | |
| PhylomeDB | P96285 | |
| BioCyc | MTBRV:RV2946C-MONOMER | |
| UniPathway | UPA00094 | |
| Proteomes | UP000001584 | |
| GO | GO:0005886 GO:0016491 GO:0031177 GO:0016747 GO:0008270 GO:0071766 GO:0071770 GO:0006633 GO:0008610 | |
| Gene3D | 1.10.1200.10 3.40.366.10 3.40.50.720 3.90.180.10 | |
| InterPro | IPR001227 IPR009081 IPR014043 IPR016035 IPR013149 IPR013154 IPR011032 IPR016036 IPR016040 IPR020801 IPR020807 IPR020843 IPR013968 IPR020806 IPR006162 | |
| Pfam | PF00698 PF08240 PF00107 PF08659 PF00550 | |
| SMART | SM00827 SM00826 SM00829 SM00822 SM00823 | |
| SUPFAM | SSF47336 SSF50129 SSF52151 SSF55048 | |
| PROSITE | PS50075 PS00012 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0071770 |
DIM/DIP cell wall layer assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008610 |
lipid biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071766 |
Actinobacterium-type cell wall biogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008610 |
lipid biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0031177 |
phosphopantetheine binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006631 |
fatty acid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006629 |
lipid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016746 |
transferase activity, transferring acyl groups |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00094 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Sirakova, TD et al. (2003) Attenuation of Mycobacterium tuberculosis by disruption of a mas-like gene or a chalcone synthase-like gene, which causes deficiency in dimycocerosyl phthiocerol synthesis. J. Bacteriol. 185 2999-3008 PubMed GONUTS page
- ↑ Mawuenyega, KG et al. (2005) Mycobacterium tuberculosis functional network analysis by global subcellular protein profiling. Mol. Biol. Cell 16 396-404 PubMed GONUTS page
- ↑ 3.0 3.1 Constant, P et al. (2002) Role of the pks15/1 gene in the biosynthesis of phenolglycolipids in the Mycobacterium tuberculosis complex. Evidence that all strains synthesize glycosylated p-hydroxybenzoic methyl esters and that strains devoid of phenolglycolipids harbor a frameshift mutation in the pks15/1 gene. J. Biol. Chem. 277 38148-58 PubMed GONUTS page
