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MYCTU:PCC6
Contents
| Species (Taxon ID) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). (83332) | |
| Gene Name(s) | accD6 | |
| Protein Name(s) | Probable propionyl-CoA carboxylase beta chain 6
PCCase Propanoyl-CoA:carbon dioxide ligase | |
| External Links | ||
| UniProt | P9WQH5 | |
| EMBL | AL123456 | |
| PIR | C70779 | |
| RefSeq | NP_216763.1 YP_006515670.1 | |
| PDB | 4L6W | |
| PDBsum | 4L6W | |
| ProteinModelPortal | P9WQH5 | |
| SMR | P9WQH5 | |
| GeneID | 13318940 887671 | |
| KEGG | mtu:Rv2247 mtv:RVBD_2247 | |
| TubercuList | Rv2247 | |
| KO | K18472 | |
| OMA | AMGVDGC | |
| PhylomeDB | P9WQH5 | |
| UniPathway | UPA00945 | |
| Proteomes | UP000001584 | |
| GO | GO:0009317 GO:0005618 GO:0003989 GO:0005524 GO:0004658 GO:0019367 GO:0040007 | |
| Gene3D | 3.90.226.10 | |
| InterPro | IPR000022 IPR029045 IPR011763 IPR011762 | |
| Pfam | PF01039 | |
| SUPFAM | SSF52096 | |
| PROSITE | PS50989 PS50980 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0003989 |
acetyl-CoA carboxylase activity |
ECO:0000314 |
F |
Figure 2 a and the legend. Materials and methods explains how to find the Km from the Henri-Michaelis-Menten equation. |
complete | |||||
|
enables |
GO:0003989 |
acetyl-CoA carboxylase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005618 |
cell wall |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019367 |
fatty acid elongation, saturated fatty acid |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009317 |
acetyl-CoA carboxylase complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003989 |
acetyl-CoA carboxylase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016874 |
ligase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004658 |
propionyl-CoA carboxylase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016874 |
ligase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Reddy, MC et al. (2014) Structure, activity, and inhibition of the Carboxyltransferase β-subunit of acetyl coenzyme A carboxylase (AccD6) from Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 58 6122-32 PubMed GONUTS page
- ↑ Wolfe, LM et al. (2010) Proteomic definition of the cell wall of Mycobacterium tuberculosis. J. Proteome Res. 9 5816-26 PubMed GONUTS page
- ↑ Kurth, DG et al. (2009) ACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteria. Microbiology (Reading, Engl.) 155 2664-75 PubMed GONUTS page
- ↑ 4.0 4.1 Daniel, J et al. (2007) AccD6, a member of the Fas II locus, is a functional carboxyltransferase subunit of the acyl-coenzyme A carboxylase in Mycobacterium tuberculosis. J. Bacteriol. 189 911-7 PubMed GONUTS page
