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MYCTU:P71815

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Species (Taxon ID) Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). (83332)
Gene Name(s) phoR (ECO:0000313 with EMBL:CCP43505.1)
Protein Name(s) ATP-binding protein (ECO:0000313 with EMBL:AIR13488.1)

OmpR family two-component system sensor histidine kinase (ECO:0000313 with EMBL:AFN48634.1) Possible two component system response sensor kinase membrane associated PhoR (ECO:0000313 with EMBL:CCP43505.1)

External Links
UniProt P71815
EMBL CP003248
CP009480
AL123456
JLDD01000006
RefSeq NP_215272.1
YP_006514105.1
SMR P71815
STRING 83332.Rv0758
PRIDE P71815
EnsemblBacteria AFN48634
CCP43505
GeneID 13318652
888775
KEGG mtu:Rv0758
mtv:RVBD_0758
PATRIC 18150202
KO K02484
OMA EVFDGPG
OrthoDB EOG6G4VQG
PhylomeDB P71815
BioCyc MTBRV:RV0758-MONOMER
Proteomes UP000001584
UP000003123
GO GO:0016021
GO:0005524
GO:0000155
Gene3D 1.10.287.130
3.30.565.10
InterPro IPR003661
IPR003660
IPR003594
IPR004358
IPR005467
IPR009082
Pfam PF00672
PF02518
PF00512
PRINTS PR00344
SMART SM00304
SM00387
SM00388
SUPFAM SSF47384
SSF55874
PROSITE PS50885
PS50109

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005886

plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10732
EcoGene:EG11614
EcoGene:EG13027
EcoGene:EG13642
EcoGene:EG14044
PANTHER:PTN001976770
UniProtKB:O69729

C

Seeded From UniProt

complete

involved_in

GO:0000160

phosphorelay signal transduction system

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001976770
UniProtKB:Q9HV31

P

Seeded From UniProt

complete

involved_in

GO:0018106

peptidyl-histidine phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004673

P

Seeded From UniProt

complete

involved_in

GO:0023014

signal transduction by protein phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0000155

P

Seeded From UniProt

complete

GO:0050789

regulation of biological process

PMID:16573683[2]

ECO:0000315

P

Table 2,3,4,5 Figure 6,7

complete

enables

GO:0000155

phosphorelay sensor kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003661
InterPro:IPR036097

F

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003660
InterPro:IPR003661
InterPro:IPR036097

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003660

C

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004358

P

Seeded From UniProt

complete

enables

GO:0016772

transferase activity, transferring phosphorus-containing groups

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004358

F

Seeded From UniProt

complete

enables

GO:0004673

protein histidine kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.13.3

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0902

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Walters, SB et al. (2006) The Mycobacterium tuberculosis PhoPR two-component system regulates genes essential for virulence and complex lipid biosynthesis. Mol. Microbiol. 60 312-30 PubMed GONUTS page