GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
MYCTU:OTSB
Contents
Species (Taxon ID) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). (83332) | |
Gene Name(s) | otsB (synonyms: otsB2) | |
Protein Name(s) | Trehalose-phosphate phosphatase
TPP Trehalose-6-phosphate phosphatase | |
External Links | ||
UniProt | P9WFZ5 | |
EMBL | AL123456 | |
PIR | C70972 | |
RefSeq | NP_217889.1 YP_006516854.1 | |
ProteinModelPortal | P9WFZ5 | |
SMR | P9WFZ5 | |
GeneID | 13316972 888137 | |
KEGG | mtu:Rv3372 mtv:RVBD_3372 | |
TubercuList | Rv3372 | |
KO | K01087 | |
OMA | GMDIMAS | |
PhylomeDB | P9WFZ5 | |
Reactome | REACT_27232 | |
UniPathway | UPA00299 | |
Proteomes | UP000001584 | |
GO | GO:0005886 GO:0000287 GO:0004805 GO:0016311 GO:0040007 GO:0005992 | |
Gene3D | 3.40.50.1000 | |
InterPro | IPR023214 IPR006379 IPR003337 | |
Pfam | PF02358 | |
SUPFAM | SSF56784 | |
TIGRFAMs | TIGR01484 TIGR00685 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
enables |
GO:0004805 |
trehalose-phosphatase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016311 |
dephosphorylation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0005992 |
trehalose biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004805 |
trehalose-phosphatase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003824 |
catalytic activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0005992 |
trehalose biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004805 |
trehalose-phosphatase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0005992 |
trehalose biosynthetic process |
Reactome:R-MTU-868688 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
Reactome:R-MTU-868608 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0005992 |
trehalose biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00299 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Murphy, HN et al. (2005) The OtsAB pathway is essential for trehalose biosynthesis in Mycobacterium tuberculosis. J. Biol. Chem. 280 14524-9 PubMed GONUTS page
- ↑ Mawuenyega, KG et al. (2005) Mycobacterium tuberculosis functional network analysis by global subcellular protein profiling. Mol. Biol. Cell 16 396-404 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Zhang, H et al. (2005) Analysis and determination of biological activity of short-chain peptides from porcine brain hydrolysate. J Pharm Biomed Anal 37 333-9 PubMed GONUTS page