MYCTU:NPD

Species (Taxon ID)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). (83332)
Gene Name(s)	cobB (ECO:0000255 with HAMAP-Rule:MF_01121) (synonyms: sir2)
Protein Name(s)	NAD-dependent protein deacylase (ECO:0000255 with HAMAP-Rule:MF_01121) Regulatory protein SIR2 homolog (ECO:0000255 with HAMAP-Rule:MF_01121)
External Links
UniProt	P9WGG3
EMBL	AL123456
PIR	H70554
RefSeq	NP_215667.1 YP_006514523.1
ProteinModelPortal	P9WGG3
SMR	P9WGG3
GeneID	13319727 886026
KEGG	mtu:Rv1151c mtv:RVBD_1151c
TubercuList	Rv1151c
KO	K12410
OMA	LIHMHGE
PhylomeDB	P9WGG3
Proteomes	UP000001584
GO	GO:0005618 GO:0005737 GO:0070403 GO:0003953 GO:0034979 GO:0036054 GO:0036055 GO:0016740 GO:0008270 GO:0006281 GO:0070213 GO:0006476
Gene3D	3.30.1600.10 3.40.50.1220
HAMAP	MF_01121
InterPro	IPR029035 IPR003000 IPR026591 IPR027546 IPR026590
PANTHER	PTHR11085
Pfam	PF02146
SUPFAM	SSF52467
PROSITE	PS50305

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0006476	protein deacetylation	PMID:21627103	ECO:0000314			P		As shown in figure 5, Acetyl CoA synthetase with a fluorescently marked chloracetyl group was lowered in fluorescent intensity when Rv1151c was added, indicating that Rv1151c deacetylated the protein.	complete CACAO 7623
involved_in	GO:0006476	protein deacetylation	PMID:21627103	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005618	cell wall	PMID:20825248	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0070213	protein auto-ADP-ribosylation	PMID:19747094	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0034979	NAD-dependent protein deacetylase activity	PMID:19747094	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0006476	protein deacetylation	PMID:19747094	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0003953	NAD+ nucleosidase activity	PMID:19747094	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0036049	peptidyl-lysine desuccinylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0036055	P		Seeded From UniProt	complete
involved_in	GO:0036049	peptidyl-lysine desuccinylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0036055	P		Seeded From UniProt	complete
involved_in	GO:0036047	peptidyl-lysine demalonylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0036054	P		Seeded From UniProt	complete
enables	GO:0036054	protein-malonyllysine demalonylase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027546	F		Seeded From UniProt	complete
enables	GO:0036055	protein-succinyllysine desuccinylase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027546	F		Seeded From UniProt	complete
enables	GO:0070403	NAD+ binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003000 InterPro:IPR027546	F		Seeded From UniProt	complete
involved_in	GO:0006476	protein deacetylation	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000334654	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000334654	C		Seeded From UniProt	complete
enables	GO:0070403	NAD+ binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000334654	F		Seeded From UniProt	complete
involved_in	GO:0036048	protein desuccinylation	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000334654	P		Seeded From UniProt	complete
enables	GO:0034979	NAD-dependent protein deacetylase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000334654	F		Seeded From UniProt	complete
enables	GO:0036055	protein-succinyllysine desuccinylase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000334654	F		Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000334654	F		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
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References

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