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MYCTU:I6X5U4
Contents
| Species (Taxon ID) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). (83332) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Uncharacterized protein (ECO:0000313 with EMBL:AFN50936.1) | |
| External Links | ||
| UniProt | I6X5U4 | |
| EMBL | CP003248 CP009480 AL123456 JLDD01000035 | |
| RefSeq | NP_217470.1 YP_006516407.1 | |
| SMR | I6X5U4 | |
| STRING | 83332.Rv2954c | |
| EnsemblBacteria | AFN50936 | |
| GeneID | 13317748 887214 | |
| KEGG | mtu:Rv2954c mtv:RVBD_2954c | |
| PATRIC | 18155159 | |
| TubercuList | Rv2954c | |
| OrthoDB | EOG6TR0CB | |
| Proteomes | UP000001584 UP000003123 | |
| GO | GO:0008171 GO:0032259 | |
| Gene3D | 3.40.50.150 | |
| InterPro | IPR029063 | |
| SUPFAM | SSF53335 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0008171 |
O-methyltransferase activity |
ECO:0000314 |
F |
Figure 4 shows that Rv2954c is responsible for the o-methylation of the hydroxyl group at position 3 of the terminal fucosyl residue of the phenolic glycolipids produced by M. tuberculosis. This conclusion is supported by the differences observed in the biochemical analyses of the glycolipid product of the Rv2954c mutant (PMM115:pPET1)compared to the same analyses of the glycolipid product of the wild-type strain. The biochemical analyses presented in figure 4 include: MALDI-TOF Mass Spec, 1D 1H-NMR, and 2D-COSY. |
complete | |||||
|
enables |
GO:0008171 |
O-methyltransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0032259 |
methylation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0008171 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Simeone, R et al. (2013) Functional characterisation of three o-methyltransferases involved in the biosynthesis of phenolglycolipids in Mycobacterium tuberculosis. PLoS ONE 8 e58954 PubMed GONUTS page
