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MYCTU:F2GHL2

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Species (Taxon ID) Mycobacterium tuberculosis KZN 4207. (478433)
Gene Name(s) clpX
Protein Name(s) ATP-dependent Clp protease ATP-binding subunit ClpX
External Links
UniProt F2GHL2
EMBL CP001662
RefSeq YP_005099994.1
ProteinModelPortal F2GHL2
SMR F2GHL2
EnsemblBacteria AEB03655
GeneID 11692983
KEGG mtk:TBSG_01526
KO K03544
OMA IMFEVPS
BioCyc MTUB478433:GH4Y-1552-MONOMER
GO GO:0005524
GO:0017111
GO:0008233
GO:0008270
GO:0006457
GO:0006508
HAMAP MF_00175
InterPro IPR003593
IPR013093
IPR019489
IPR004487
IPR027417
IPR010603
Pfam PF07724
PF10431
PF06689
SMART SM00382
SM01086
SM00994
SUPFAM SSF52540
TIGRFAMs TIGR00382

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0006508

proteolysis

PMID:21736903[1]

IEP: Inferred from Expression Pattern

P

Figure 2 shows that under grow conditions where clpX is added, it inhibits the ftsZ protein which is the chief modulator of cell division. ftsZ degradation by clpX shows its proteolysis properties.

complete

GO:0000166

nucleotide binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

Seeded From UniProt

complete

GO:0000166

nucleotide binding

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004487
InterPro:IPR013093

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00175

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

GO:0006457

protein folding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004487

P

Seeded From UniProt

complete

GO:0006457

protein folding

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00175

P

Seeded From UniProt

complete

GO:0006508

proteolysis

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0645

P

Seeded From UniProt

complete

GO:0008233

peptidase activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0645

F

Seeded From UniProt

complete

GO:0008270

zinc ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010603

F

Seeded From UniProt

complete

GO:0017111

nucleoside-triphosphatase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003593

F

Seeded From UniProt

complete

GO:0046872

metal ion binding

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

GO:0046983

protein dimerization activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010603

F

Seeded From UniProt

complete

GO:0051082

unfolded protein binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004487

F

Seeded From UniProt

complete

GO:0051082

unfolded protein binding

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00175

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Baker, TA & Sauer, RT (2012) ClpXP, an ATP-powered unfolding and protein-degradation machine. Biochim. Biophys. Acta 1823 15-28 PubMed GONUTS page