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MYCSM:ALR

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Species (Taxon ID) Mycobacterium smegmatis. (1772)
Gene Name(s) alr (synonyms: alrA)
Protein Name(s) Alanine racemase (ECO:0000255 with HAMAP-Rule:MF_01201)
External Links
UniProt P94967
EMBL U70872
ProteinModelPortal P94967
SMR P94967
UniPathway UPA00042
GO GO:0008784
GO:0030170
GO:0030632
GO:0046677
Gene3D 2.40.37.10
3.20.20.10
HAMAP MF_01201
InterPro IPR000821
IPR009006
IPR011079
IPR001608
IPR020622
IPR029066
Pfam PF00842
PF01168
PRINTS PR00992
SMART SM01005
SUPFAM SSF50621
SSF51419
TIGRFAMs TIGR00492
PROSITE PS00395

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0008784

alanine racemase activity

PMID:9260945[1]

ECO:0000314

F

Figure 5: Depicts alanine racemase activity among different strains. Strain GPM14 shows marked overproduction of d-alanine racemase as a result of a single base change from T -> G in the alrA gene promoter as described in the "Results" section.

complete
CACAO 4949

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009006

F

Seeded From UniProt

complete

involved_in

GO:0006522

alanine metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000821

P

Seeded From UniProt

complete

enables

GO:0008784

alanine racemase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000821

F

Seeded From UniProt

complete

enables

GO:0008784

alanine racemase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:5.1.1.1

F

Seeded From UniProt

complete

involved_in

GO:0006522

alanine metabolic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000100948

P

Seeded From UniProt

complete

enables

GO:0008784

alanine racemase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000100948

F

Seeded From UniProt

complete

enables

GO:0030170

pyridoxal phosphate binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000100948

F

Seeded From UniProt

complete

involved_in

GO:0046677

response to antibiotic

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0046

P

Seeded From UniProt

complete

enables

GO:0016853

isomerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0413

F

Seeded From UniProt

complete

involved_in

GO:0030632

D-alanine biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00042

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Cáceres, NE et al. (1997) Overexpression of the D-alanine racemase gene confers resistance to D-cycloserine in Mycobacterium smegmatis. J. Bacteriol. 179 5046-55 PubMed GONUTS page