MOUSE:ZP3R

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Zp3r (synonyms: Sp56)
Protein Name(s)	Zona pellucida sperm-binding protein 3 receptor Sperm fertilization protein 56 sp56
External Links
UniProt	Q60736
EMBL	U17108
CCDS	CCDS15257.1
PIR	A56740
UniGene	Mm.4644
ProteinModelPortal	Q60736
SMR	Q60736
PaxDb	Q60736
PRIDE	Q60736
MGI	MGI:104965
eggNOG	NOG150577
HOGENOM	HOG000015324
HOVERGEN	HBG004657
InParanoid	Q60736
PhylomeDB	Q60736
PRO	PR:Q60736
Proteomes	UP000000589
CleanEx	MM_ZP3R
Genevestigator	Q60736
GO	GO:0043160 GO:0043159 GO:0001669 GO:0044297 GO:0002081 GO:0005886 GO:0002199 GO:0007339 GO:0007338
InterPro	IPR000436
Pfam	PF00084
SMART	SM00032
SUPFAM	SSF57535
PROSITE	PS50923

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0043159	acrosomal matrix	PMID:11133656^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007339	binding of sperm to zona pellucida	PMID:11417900^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007339	binding of sperm to zona pellucida	PMID:7604284^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:11417900^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0002081	outer acrosomal membrane	PMID:11417900^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0044297	cell body	PMID:21880732^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000019)	Seeded From UniProt	complete
part_of	GO:0043159	acrosomal matrix	PMID:11784086^[5]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000019)	Seeded From UniProt	complete
part_of	GO:0043159	acrosomal matrix	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:727846	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007339	binding of sperm to zona pellucida	PMID:7604284^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007339	binding of sperm to zona pellucida	PMID:21880732^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007339	binding of sperm to zona pellucida	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:727846	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007338	single fertilization	PMID:9890753^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0002199	zona pellucida receptor complex	PMID:21880732^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0001669	acrosomal vesicle	PMID:16540102^[7]	ECO:0005804	immunofluorescence evidence used in manual assertion		C	part_of:(CL:0000019)	Seeded From UniProt	complete
part_of	GO:0001669	acrosomal vesicle	PMID:9890753^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0001669	acrosomal vesicle	PMID:23976951^[8]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0001669	acrosomal vesicle	PMID:21640725^[9]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000019)	Seeded From UniProt	complete
involved_in	GO:0007338	single fertilization	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0278	P		Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0968	C		Seeded From UniProt	complete
part_of	GO:0043160	acrosomal lumen	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0005	C		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ Kim, KS et al. (2001) Mouse sperm protein sp56 is a component of the acrosomal matrix. Biol. Reprod. 64 36-43 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Cohen, N & Wassarman, PM (2001) Association of egg zona pellucida glycoprotein mZP3 with sperm protein sp56 during fertilization in mice. Int. J. Dev. Biol. 45 569-76 PubMed GONUTS page
↑ ^3.0 ^3.1 Bookbinder, LH et al. (1995) Tissue- and species-specific expression of sp56, a mouse sperm fertilization protein. Science 269 86-9 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Dun, MD et al. (2011) The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction. J. Biol. Chem. 286 36875-87 PubMed GONUTS page
↑ Travis, AJ et al. (2001) Expression and localization of caveolin-1, and the presence of membrane rafts, in mouse and Guinea pig spermatozoa. Dev. Biol. 240 599-610 PubMed GONUTS page
↑ ^6.0 ^6.1 Hardy, CM & Mobbs, KJ (1999) Expression of recombinant mouse sperm protein sp56 and assessment of its potential for use as an antigen in an immunocontraceptive vaccine. Mol. Reprod. Dev. 52 216-24 PubMed GONUTS page
↑ Moreno, RD et al. (2006) Assembly of spermatid acrosome depends on microtubule organization during mammalian spermiogenesis. Dev. Biol. 293 218-27 PubMed GONUTS page
↑ Colley, SM et al. (2013) Loss of the nuclear receptor corepressor SLIRP compromises male fertility. PLoS ONE 8 e70700 PubMed GONUTS page
↑ Arimitsu, N et al. (2011) p125/Sec23-interacting protein (Sec23ip) is required for spermiogenesis. FEBS Lett. 585 2171-6 PubMed GONUTS page

[PMID:11133656-1] Kim, KS et al. (2001) Mouse sperm protein sp56 is a component of the acrosomal matrix. Biol. Reprod. 64 36-43 PubMed GONUTS page

[PMID:11417900-2] 2.0 ^2.1 ^2.2 Cohen, N & Wassarman, PM (2001) Association of egg zona pellucida glycoprotein mZP3 with sperm protein sp56 during fertilization in mice. Int. J. Dev. Biol. 45 569-76 PubMed GONUTS page

[PMID:7604284-3] 3.0 ^3.1 Bookbinder, LH et al. (1995) Tissue- and species-specific expression of sp56, a mouse sperm fertilization protein. Science 269 86-9 PubMed GONUTS page

[PMID:21880732-4] 4.0 ^4.1 ^4.2 Dun, MD et al. (2011) The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction. J. Biol. Chem. 286 36875-87 PubMed GONUTS page

[PMID:11784086-5] Travis, AJ et al. (2001) Expression and localization of caveolin-1, and the presence of membrane rafts, in mouse and Guinea pig spermatozoa. Dev. Biol. 240 599-610 PubMed GONUTS page

[PMID:9890753-6] 6.0 ^6.1 Hardy, CM & Mobbs, KJ (1999) Expression of recombinant mouse sperm protein sp56 and assessment of its potential for use as an antigen in an immunocontraceptive vaccine. Mol. Reprod. Dev. 52 216-24 PubMed GONUTS page

[PMID:16540102-7] Moreno, RD et al. (2006) Assembly of spermatid acrosome depends on microtubule organization during mammalian spermiogenesis. Dev. Biol. 293 218-27 PubMed GONUTS page

[PMID:23976951-8] Colley, SM et al. (2013) Loss of the nuclear receptor corepressor SLIRP compromises male fertility. PLoS ONE 8 e70700 PubMed GONUTS page

[PMID:21640725-9] Arimitsu, N et al. (2011) p125/Sec23-interacting protein (Sec23ip) is required for spermiogenesis. FEBS Lett. 585 2171-6 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

MOUSE:ZP3R

Contents

Annotations

Notes

References

a

b

c

e

g

m

o

p

r

s

v

z

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools