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MOUSE:ZP1
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Zp1 | |
| Protein Name(s) | Zona pellucida sperm-binding protein 1
Zona pellucida glycoprotein 1 Zp-1 Processed zona pellucida sperm-binding protein 1 | |
| External Links | ||
| UniProt | Q62005 | |
| EMBL | U24230 U24227 U24228 U24229 U20448 | |
| CCDS | CCDS37918.1 | |
| PIR | I46382 | |
| RefSeq | NP_033606.2 | |
| UniGene | Mm.24767 | |
| ProteinModelPortal | Q62005 | |
| SMR | Q62005 | |
| PhosphoSite | Q62005 | |
| PRIDE | Q62005 | |
| Ensembl | ENSMUST00000025641 | |
| GeneID | 22786 | |
| KEGG | mmu:22786 | |
| UCSC | uc008grh.2 | |
| CTD | 22917 | |
| MGI | MGI:103073 | |
| eggNOG | NOG39535 | |
| GeneTree | ENSGT00530000063096 | |
| HOGENOM | HOG000118071 | |
| HOVERGEN | HBG036289 | |
| InParanoid | Q62005 | |
| OMA | GCHVLEK | |
| OrthoDB | EOG7D2FDC | |
| PhylomeDB | Q62005 | |
| TreeFam | TF332794 | |
| Reactome | REACT_199072 | |
| NextBio | 303363 | |
| PRO | PR:Q62005 | |
| Proteomes | UP000000589 | |
| Bgee | Q62005 | |
| CleanEx | MM_ZP1 | |
| Genevestigator | Q62005 | |
| GO | GO:0031012 GO:0005794 GO:0016021 GO:0005886 GO:0005578 GO:0030141 GO:0007338 | |
| Gene3D | 4.10.110.10 | |
| InterPro | IPR000519 IPR017957 IPR001507 IPR017977 | |
| Pfam | PF00088 PF00100 | |
| PRINTS | PR00023 | |
| SMART | SM00018 SM00241 | |
| SUPFAM | SSF57492 | |
| PROSITE | PS00025 PS51448 PS00682 PS51034 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0062023 |
collagen-containing extracellular matrix |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007338 |
single fertilization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
| GO:0007339 |
binding of sperm to zona pellucida |
ECO:0000314 |
P |
Fig. 1 An electron micrograph shows the internal structure of Zp. |
complete | |||||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
Contributes to |
GO:0007339 |
binding of sperm to zona pellucida |
ECO:0000314 |
P |
The Z2 element of the Z protein acts as a secondary sperm receptor and is expressed primary to ovulation of the oocyte. The Z2 element consists of 745 amino acids. |
complete | ||||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 El-Mestrah, M et al. (2002) Subcellular distribution of ZP1, ZP2, and ZP3 glycoproteins during folliculogenesis and demonstration of their topographical disposition within the zona matrix of mouse ovarian oocytes. Biol. Reprod. 66 866-76 PubMed GONUTS page
- ↑ Burkart, AD et al. (2012) Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy. J. Cell Biol. 197 37-44 PubMed GONUTS page
