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MOUSE:VPS52

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Vps52
Protein Name(s) Vacuolar protein sorting-associated protein 52 homolog
External Links
UniProt Q8C754
EMBL AK051732
AK052523
AF100956
AF110520
BC063329
CCDS CCDS37574.1
RefSeq NP_766208.2
UniGene Mm.448614
Mm.485758
ProteinModelPortal Q8C754
PhosphoSite Q8C754
MaxQB Q8C754
PaxDb Q8C754
PRIDE Q8C754
Ensembl ENSMUST00000025178
GeneID 224705
KEGG mmu:224705
UCSC uc008cam.1
CTD 6293
MGI MGI:1330304
eggNOG NOG296730
GeneTree ENSGT00390000008815
HOGENOM HOG000020960
HOVERGEN HBG052966
InParanoid Q8C754
OMA THYLEVP
OrthoDB EOG7HTHGH
PhylomeDB Q8C754
TreeFam TF314937
ChiTaRS Vps52
NextBio 377320
PRO PR:Q8C754
Proteomes UP000000589
Bgee Q8C754
CleanEx MM_VPS52
ExpressionAtlas Q8C754
Genevestigator Q8C754
GO GO:0010008
GO:0005794
GO:0010668
GO:0048611
GO:0015031
InterPro IPR007258
PANTHER PTHR14190
Pfam PF04129

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:1990745

EARP complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8N1B4

C

Seeded From UniProt

complete

part_of

GO:0055037

recycling endosome

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8N1B4

C

Seeded From UniProt

complete

involved_in

GO:0032456

endocytic recycling

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8N1B4

P

Seeded From UniProt

complete

involved_in

GO:0042147

retrograde transport, endosome to Golgi

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000367098
SGD:S000002892

P

Seeded From UniProt

complete

involved_in

GO:0032456

endocytic recycling

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0031710
PANTHER:PTN000367098
UniProtKB:Q8N1B4

P

Seeded From UniProt

complete

enables

GO:0019905

syntaxin binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000367098
UniProtKB:Q8N1B4
WB:WBGene00007059

F

Seeded From UniProt

complete

enables

GO:0017137

Rab GTPase binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0031710
PANTHER:PTN000367098
WB:WBGene00007059

F

Seeded From UniProt

complete

involved_in

GO:0007041

lysosomal transport

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001021633
UniProtKB:Q8N1B4

P

Seeded From UniProt

complete

involved_in

GO:0006896

Golgi to vacuole transport

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000367098
SGD:S000002892

P

Seeded From UniProt

complete

part_of

GO:0000938

GARP complex

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0031710
PANTHER:PTN000367098
TAIR:locus:2032343
UniProtKB:Q8N1B4
WB:WBGene00007059

C

Seeded From UniProt

complete

part_of

GO:1990745

EARP complex

PMID:25799061[2]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8N1B4

C

Seeded From UniProt

complete

part_of

GO:1990745

EARP complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8N1B4

C

Seeded From UniProt

complete

part_of

GO:0055037

recycling endosome

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8N1B4

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0048611

embryonic ectodermal digestive tract development

PMID:23142660[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8N1B4

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0032456

endocytic recycling

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8N1B4

P

Seeded From UniProt

complete

enables

GO:0019905

syntaxin binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8N1B4

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:25799061[2]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8N1B4

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0010668

ectodermal cell differentiation

PMID:23142660[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007041

lysosomal transport

PMID:25799061[2]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8N1B4

P

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8N1B4

C

Seeded From UniProt

complete

part_of

GO:0000938

GARP complex

PMID:25799061[2]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8N1B4

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0042147

C

Seeded From UniProt

complete

part_of

GO:1990745

EARP complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8N1B4
ensembl:ENSP00000409952

C

Seeded From UniProt

complete

part_of

GO:0055037

recycling endosome

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8N1B4
ensembl:ENSP00000409952

C

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8N1B4
ensembl:ENSP00000409952

C

Seeded From UniProt

complete

involved_in

GO:0032456

endocytic recycling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8N1B4
ensembl:ENSP00000409952

P

Seeded From UniProt

complete

enables

GO:0019905

syntaxin binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8N1B4
ensembl:ENSP00000409952

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8N1B4
ensembl:ENSP00000409952

C

Seeded From UniProt

complete

involved_in

GO:0007041

lysosomal transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8N1B4
ensembl:ENSP00000409952

P

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8N1B4
ensembl:ENSP00000409952

C

Seeded From UniProt

complete

part_of

GO:0000938

GARP complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8N1B4
ensembl:ENSP00000409952

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333
UniProtKB-SubCell:SL-0132

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653

P

Seeded From UniProt

complete

part_of

GO:0005768

endosome

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0967

C

Seeded From UniProt

complete

part_of

GO:0055037

recycling endosome

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0232

C

Seeded From UniProt

complete

part_of

GO:0010008

endosome membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0100

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Schindler, C et al. (2015) EARP is a multisubunit tethering complex involved in endocytic recycling. Nat. Cell Biol. 17 639-50 PubMed GONUTS page
  3. 3.0 3.1 Sugimoto, M et al. (2012) Molecular identification of t(w5): Vps52 promotes pluripotential cell differentiation through cell-cell interactions. Cell Rep 2 1363-74 PubMed GONUTS page