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MOUSE:V9GXT3

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) No Information Provided.
Protein Name(s) Protein Nav2 (ECO:0000313 with Ensembl:ENSMUSP00000139309)
External Links
UniProt V9GXT3
EMBL AC107862
AC114612
AC119804
AC119848
AC120854
RefSeq NP_001104486.1
UniGene Mm.333881
Mm.471488
ProteinModelPortal V9GXT3
SMR V9GXT3
STRING 10090.ENSMUSP00000067448
iPTMnet V9GXT3
MaxQB V9GXT3
PaxDb V9GXT3
Ensembl ENSMUST00000183659
GeneID 78286
KEGG mmu:78286
UCSC uc057ahh.1
CTD 89797
MGI MGI:2183691
eggNOG ENOG410IGVF
ENOG410XRG8
GeneTree ENSGT00530000063334
KO K19483
ChiTaRS Nav2
Proteomes UP000000589
ExpressionAtlas V9GXT3
GO GO:0005614
GO:0005654
GO:0005578
GO:0008201
GO:0021563
GO:0007626
GO:0021554
GO:0003025
GO:0007608
GO:0007605
GO:0021564
Gene3D 1.10.418.10
3.40.50.300
InterPro IPR003593
IPR001715
IPR027417
Pfam PF00307
SMART SM00382
SM00033
SUPFAM SSF47576
SSF52540
PROSITE PS50021

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0007399

nervous system development

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000980100
RGD:619778

P

Seeded From UniProt

complete

part_of

GO:0031012

extracellular matrix

PMID:18757743[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

GO:0021695

cerebellar cortex development

PMID:21419114[3]

ECO:0000315

P

Figure 2. Nav2- Mutant displays improper cerebellum development compared to wild types.

complete
CACAO 6431

acts_upstream_of_or_within

GO:0021564

vagus nerve development

PMID:20184720[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3054375

P

results_in_development_of:(EMAPA:17272)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0021563

glossopharyngeal nerve development

PMID:20184720[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3054375

P

results_in_development_of:(EMAPA:17268)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0021554

optic nerve development

PMID:15158073[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3054375

P

results_in_development_of:(EMAPA:17575)

Seeded From UniProt

complete

enables

GO:0008201

heparin binding

PMID:18757743[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007626

locomotory behavior

PMID:15158073[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3054375

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007608

sensory perception of smell

PMID:15158073[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3054375

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007605

sensory perception of sound

PMID:15158073[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3054375

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007399

nervous system development

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:619778

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8IVL1

C

Seeded From UniProt

complete

part_of

GO:0005614

interstitial matrix

PMID:18757743[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(EMAPA:35854)|part_of:(EMAPA:35493)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0003025

regulation of systemic arterial blood pressure by baroreceptor feedback

PMID:20184720[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3054375

P

Seeded From UniProt

complete

involved_in

GO:0022008

neurogenesis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039041

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 Manabe, R et al. (2008) Transcriptome-based systematic identification of extracellular matrix proteins. Proc. Natl. Acad. Sci. U.S.A. 105 12849-54 PubMed GONUTS page
  3. McNeill, EM et al. (2011) Nav2 hypomorphic mutant mice are ataxic and exhibit abnormalities in cerebellar development. Dev. Biol. 353 331-43 PubMed GONUTS page
  4. 4.0 4.1 4.2 McNeill, EM et al. (2010) Nav2 is necessary for cranial nerve development and blood pressure regulation. Neural Dev 5 6 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Peeters, PJ et al. (2004) Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53. Brain Res. Dev. Brain Res. 150 89-101 PubMed GONUTS page