MOUSE:TRAM2

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Tram2
Protein Name(s)	Translocating chain-associated membrane protein 2
External Links
UniProt	Q924Z5
EMBL	AY029530 AK082751 BC018212
CCDS	CCDS14846.1
RefSeq	NP_803128.1
UniGene	Mm.185680 Mm.273241
STRING	10090.ENSMUSP00000047992
PhosphoSite	Q924Z5
MaxQB	Q924Z5
PRIDE	Q924Z5
Ensembl	ENSMUST00000037998
GeneID	170829
KEGG	mmu:170829
UCSC	uc007alg.1
CTD	9697
MGI	MGI:1924817
eggNOG	NOG292300
GeneTree	ENSGT00510000046470
HOGENOM	HOG000007494
HOVERGEN	HBG054402
InParanoid	Q924Z5
OMA	FIQPQYN
OrthoDB	EOG7ZPNKC
PhylomeDB	Q924Z5
TreeFam	TF314319
NextBio	370495
PRO	PR:Q924Z5
Proteomes	UP000000589
Bgee	Q924Z5
Genevestigator	Q924Z5
GO	GO:0016021 GO:0032964 GO:0015031
InterPro	IPR006634 IPR013599 IPR016447
Pfam	PF08390 PF03798
PIRSF	PIRSF005449
SMART	SM00724
PROSITE	PS50922

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:2000489	regulation of hepatic stellate cell activation	PMID:14749390	ECO:0000314			P		Figure 2. (and 1)TRAM2 is expressed in activated haptic stellate cells	complete CACAO 9204
	GO:0032965	regulation of collagen biosynthetic process	PMID:14749390	ECO:0000315			P		Figure 4 &5. Mutant TRAM2 inhibits collagen synthesis by hepatic stellate cells	complete CACAO 9205
involved_in	GO:0045048	protein insertion into ER membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q15035	P		Seeded From UniProt	complete
part_of	GO:0005791	rough endoplasmic reticulum		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000962047 WB:WBGene00007696	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045048	protein insertion into ER membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15035	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032964	collagen biosynthetic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15035	P		Seeded From UniProt	complete
involved_in	GO:0045048	protein insertion into ER membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15035 ensembl:ENSP00000182527	P		Seeded From UniProt	complete
involved_in	GO:0032964	collagen biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15035 ensembl:ENSP00000182527	P		Seeded From UniProt	complete
involved_in	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016447	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006634	C		Seeded From UniProt	complete
involved_in	GO:0015031	protein transport	GO_REF:0000037 GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0653 UniProtKB-KW:KW-0811	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C		Seeded From UniProt	complete
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References

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