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MOUSE:TOM22
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Tomm22 (synonyms: Tom22) | |
| Protein Name(s) | Mitochondrial import receptor subunit TOM22 homolog
Translocase of outer membrane 22 kDa subunit homolog | |
| External Links | ||
| UniProt | Q9CPQ3 | |
| EMBL | AK008133 AK009868 AK013471 AK049442 AK150360 AK152843 AK167803 BC056920 | |
| CCDS | CCDS27646.1 | |
| RefSeq | NP_766197.2 | |
| UniGene | Mm.246435 Mm.485795 | |
| ProteinModelPortal | Q9CPQ3 | |
| SMR | Q9CPQ3 | |
| BioGrid | 230178 | |
| IntAct | Q9CPQ3 | |
| MINT | MINT-1844683 | |
| STRING | 10090.ENSMUSP00000023062 | |
| iPTMnet | Q9CPQ3 | |
| PhosphoSitePlus | Q9CPQ3 | |
| EPD | Q9CPQ3 | |
| MaxQB | Q9CPQ3 | |
| PaxDb | Q9CPQ3 | |
| PeptideAtlas | Q9CPQ3 | |
| PRIDE | Q9CPQ3 | |
| TopDownProteomics | Q9CPQ3 | |
| Ensembl | ENSMUST00000023062 | |
| GeneID | 223696 | |
| KEGG | mmu:223696 | |
| UCSC | uc007wud.1 | |
| CTD | 56993 | |
| MGI | MGI:2450248 | |
| eggNOG | KOG4111 ENOG41122K3 | |
| GeneTree | ENSGT00390000016475 | |
| HOGENOM | HOG000067816 | |
| HOVERGEN | HBG061819 | |
| InParanoid | Q9CPQ3 | |
| KO | K17769 | |
| OMA | FYTFSCN | |
| OrthoDB | EOG091G0XN1 | |
| PhylomeDB | Q9CPQ3 | |
| TreeFam | TF106201 | |
| Reactome | [www.reactome.org/content/detail/R-MMU-5205685 R-MMU-5205685] | |
| PRO | PR:Q9CPQ3 | |
| Proteomes | UP000000589 | |
| Bgee | ENSMUSG00000022427 | |
| Genevisible | Q9CPQ3 | |
| GO | GO:0016021 GO:0031307 GO:0016020 GO:0005743 GO:0005742 GO:0005739 GO:0008320 GO:0030150 GO:0045040 | |
| InterPro | IPR005683 | |
| PANTHER | PTHR12504:SF3 | |
| Pfam | PF04281 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005741 |
mitochondrial outer membrane |
ECO:0000314 |
C |
As seen on figure 6, localization of TOM22 is to the outer mitochondrial membrane (OMM). Mitochondrial import receptor subunit TOM22 Mouse |
complete | |||||
|
involved_in |
GO:0006626 |
protein targeting to mitochondrion |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0051204 |
protein insertion into mitochondrial membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:1303260 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0045040 |
protein insertion into mitochondrial outer membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0043065 |
positive regulation of apoptotic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:1303260 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008320 |
protein transmembrane transporter activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:1303260 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0006626 |
protein targeting to mitochondrion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:1303260 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005743 |
mitochondrial inner membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005742 |
mitochondrial outer membrane translocase complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005742 |
mitochondrial outer membrane translocase complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:1303260 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:1303260 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0071806 |
protein transmembrane transport |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0008320 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0071806 |
protein transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0008320 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q549C5 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051204 |
protein insertion into mitochondrial membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q75Q41 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043065 |
positive regulation of apoptotic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q75Q41 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008320 |
protein transmembrane transporter activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q75Q41 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006626 |
protein targeting to mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q75Q41 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005742 |
mitochondrial outer membrane translocase complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q75Q41 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q75Q41 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045040 |
protein insertion into mitochondrial outer membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9NS69 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9NS69 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005742 |
mitochondrial outer membrane translocase complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9NS69 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9NS69 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005741 |
mitochondrial outer membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006886 |
intracellular protein transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015031 |
protein transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005741 |
mitochondrial outer membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Safdar, A et al. (2011) Exercise increases mitochondrial PGC-1alpha content and promotes nuclear-mitochondrial cross-talk to coordinate mitochondrial biogenesis. J. Biol. Chem. 286 10605-17 PubMed GONUTS page
- ↑ Da Cruz, S et al. (2003) Proteomic analysis of the mouse liver mitochondrial inner membrane. J. Biol. Chem. 278 41566-71 PubMed GONUTS page
- ↑ Pagliarini, DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134 112-23 PubMed GONUTS page
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- GO:0043065 ! positive regulation of apoptotic process
- GO:0045040 ! protein insertion into mitochondrial outer membrane
- GO:0051204 ! protein insertion into mitochondrial membrane
- GO:0006626 ! protein targeting to mitochondrion
- GO:0071806 ! protein transmembrane transport
- GO:0008320 ! protein transmembrane transporter activity
- GO:0015031 ! protein transport
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