GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
MOUSE:TN13B
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Tnfsf13b (synonyms: Baff) | |
| Protein Name(s) | Tumor necrosis factor ligand superfamily member 13B
B-cell-activating factor BAFF Tumor necrosis factor ligand superfamily member 13b, membrane form Tumor necrosis factor ligand superfamily member 13b, soluble form | |
| External Links | ||
| UniProt | Q9WU72 | |
| EMBL | AF119383 AF352245 AY290823 CH466566 BC106840 | |
| CCDS | CCDS22094.1 | |
| RefSeq | NP_296371.1 XP_006508837.1 | |
| UniGene | Mm.28835 | |
| ProteinModelPortal | Q9WU72 | |
| SMR | Q9WU72 | |
| BioGrid | 204896 | |
| STRING | 10090.ENSMUSP00000033892 | |
| PhosphoSite | Q9WU72 | |
| PRIDE | Q9WU72 | |
| Ensembl | ENSMUST00000033892 | |
| GeneID | 24099 | |
| KEGG | mmu:24099 | |
| UCSC | uc009kup.1 uc009kuq.1 | |
| CTD | 10673 | |
| MGI | MGI:1344376 | |
| eggNOG | NOG47835 | |
| GeneTree | ENSGT00530000063837 | |
| HOGENOM | HOG000036810 | |
| HOVERGEN | HBG061472 | |
| InParanoid | Q9WU72 | |
| KO | K05476 | |
| OrthoDB | EOG7T4MM3 | |
| PhylomeDB | Q9WU72 | |
| TreeFam | TF332331 | |
| NextBio | 304105 | |
| PRO | PR:Q9WU72 | |
| Proteomes | UP000000589 | |
| Bgee | Q9WU72 | |
| ExpressionAtlas | Q9WU72 | |
| Genevestigator | Q9WU72 | |
| GO | GO:0005615 GO:0016021 GO:0048471 GO:0005886 GO:0031296 GO:0001782 GO:0006955 GO:0048305 GO:0030890 GO:0002636 GO:0042102 GO:0050776 GO:0031295 | |
| Gene3D | 2.60.120.40 | |
| InterPro | IPR006052 IPR008983 | |
| Pfam | PF00229 | |
| SMART | SM00207 | |
| SUPFAM | SSF49842 | |
| PROSITE | PS50049 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
acts_upstream_of_or_within |
GO:0050776 |
regulation of immune response |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2387426 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0050776 |
regulation of immune response |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2387426 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0048305 |
immunoglobulin secretion |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:88337 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0042102 |
positive regulation of T cell proliferation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0042102 |
positive regulation of T cell proliferation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0031296 |
B cell costimulation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0031295 |
T cell costimulation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0031295 |
T cell costimulation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0030890 |
positive regulation of B cell proliferation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0030890 |
positive regulation of B cell proliferation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0002636 |
positive regulation of germinal center formation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2387426 |
P |
regulates_o_results_in_formation_of:(EMAPA:35803) |
Seeded From UniProt |
complete | |
|
acts_upstream_of_or_within |
GO:0001782 |
B cell homeostasis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2387426 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005125 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9Y275 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030890 |
positive regulation of B cell proliferation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9Y275 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9Y275 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005164 |
tumor necrosis factor receptor binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006955 |
immune response |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005125 |
cytokine activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Ye, Q et al. (2004) BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses. Eur. J. Immunol. 34 2750-9 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Rahman, ZS et al. (2003) Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice. J. Exp. Med. 198 1157-69 PubMed GONUTS page
- ↑ Qian, Y et al. (2004) Act1, a negative regulator in CD40- and BAFF-mediated B cell survival. Immunity 21 575-87 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Ng, LG et al. (2004) B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells. J. Immunol. 173 807-17 PubMed GONUTS page
e
g
i
p
r
