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MOUSE:TMED2
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Tmed2 (synonyms: Rnp24, Sid394) | |
| Protein Name(s) | Transmembrane emp24 domain-containing protein 2
COPI-coated vesicle membrane protein p24 Membrane protein p24A Sid 394 p24 family protein beta-1 p24beta1 | |
| External Links | ||
| UniProt | Q9R0Q3 | |
| EMBL | AB025218 BC083140 | |
| CCDS | CCDS19679.1 | |
| RefSeq | NP_062744.1 XP_003945495.1 | |
| UniGene | Mm.325307 Mm.425279 | |
| IntAct | Q9R0Q3 | |
| MINT | MINT-1863429 | |
| STRING | 10090.ENSMUSP00000089769 | |
| PhosphoSite | Q9R0Q3 | |
| MaxQB | Q9R0Q3 | |
| PaxDb | Q9R0Q3 | |
| PRIDE | Q9R0Q3 | |
| Ensembl | ENSMUST00000060226 | |
| GeneID | 100862175 56334 | |
| KEGG | mmu:100862175 mmu:56334 | |
| UCSC | uc008zqa.1 | |
| CTD | 10959 | |
| MGI | MGI:1929269 | |
| eggNOG | NOG271196 | |
| GeneTree | ENSGT00670000097656 | |
| HOGENOM | HOG000160229 | |
| HOVERGEN | HBG105106 | |
| InParanoid | Q9R0Q3 | |
| OMA | DYSFTAH | |
| OrthoDB | EOG7RFTJP | |
| PhylomeDB | Q9R0Q3 | |
| TreeFam | TF313000 | |
| Reactome | REACT_196517 | |
| NextBio | 312318 | |
| PRO | PR:Q9R0Q3 | |
| Proteomes | UP000000589 | |
| Bgee | Q9R0Q3 | |
| CleanEx | MM_TMED2 | |
| ExpressionAtlas | Q9R0Q3 | |
| Genevestigator | Q9R0Q3 | |
| GO | GO:0030137 GO:0030663 GO:0005783 GO:0005789 GO:0005793 GO:0033116 GO:0005794 GO:0032580 GO:0016021 GO:0042589 GO:0048598 GO:0007030 GO:0001893 GO:0034260 GO:0072661 GO:0016192 | |
| InterPro | IPR009038 IPR015720 | |
| PANTHER | PTHR22811 | |
| Pfam | PF01105 | |
| SUPFAM | SSF101576 | |
| PROSITE | PS50866 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0060716 |
labyrinthine layer blood vessel development |
ECO:0000315 |
P |
Fig 2. Absence of the labyrinth layer in the mutant phenotype. More specifically as seen in Fig.2 D-F there is no invagination of the allantois into the chorion, which is necessary for the formation of the labyrinth layer, in the mutants like there is in the wild type. |
complete | |||||
|
involved_in |
GO:0060716 |
labyrinthine layer blood vessel development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042589 |
zymogen granule membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0072659 |
protein localization to plasma membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0048598 |
embryonic morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034260 |
negative regulation of GTPase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030137 |
COPI-coated vesicle |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007030 |
Golgi organization |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005793 |
endoplasmic reticulum-Golgi intermediate compartment |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001893 |
maternal placenta development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030134 |
COPII-coated ER to Golgi transport vesicle |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000516376 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007030 |
Golgi organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0069242 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006888 |
endoplasmic reticulum to Golgi vesicle-mediated transport |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0029709 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006886 |
intracellular protein transport |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000516376 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000516376 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005793 |
endoplasmic reticulum-Golgi intermediate compartment |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0061492 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0264389 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042589 |
zymogen granule membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:69243 |
C |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0036342 |
post-anal tail morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:4343479 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0036342 |
post-anal tail morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:4343479 |
P |
has_participant:(EMAPA:16748) |
Seeded From UniProt |
complete | |
|
acts_upstream_of_or_within |
GO:0035264 |
multicellular organism growth |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:4343479 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0032525 |
somite rostral/caudal axis specification |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:4456438 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0030137 |
COPI-coated vesicle |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:69243 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:69243 |
C |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0010628 |
positive regulation of gene expression |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:4456438 |
P |
has_regulation_target:(MGI:MGI:1913926)|has_regulation_target:(MGI:MGI:1914761)|has_regulation_target:(MGI:MGI:1915831) |
Seeded From UniProt |
complete | |
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005793 |
endoplasmic reticulum-Golgi intermediate compartment |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003674 |
molecular_function |
ECO:0000307 |
no biological data found used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0001947 |
heart looping |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:4343479 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0001892 |
embryonic placenta development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:4456438 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0001843 |
neural tube closure |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:4456438 |
P |
has_participant:(EMAPA:16530) |
Seeded From UniProt |
complete | |
|
acts_upstream_of_or_within |
GO:0001756 |
somitogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:4456438 |
P |
has_participant:(EMAPA:16184)|has_participant:(EMAPA:16172) |
Seeded From UniProt |
complete | |
|
acts_upstream_of_or_within |
GO:0001701 |
in utero embryonic development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:4343479 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0072659 |
protein localization to plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q15363 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q15363 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0034260 |
negative regulation of GTPase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q15363 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007030 |
Golgi organization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q15363 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006886 |
intracellular protein transport |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q15363 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q15363 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005793 |
endoplasmic reticulum-Golgi intermediate compartment |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q15363 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q15363 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0042589 |
zymogen granule membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q63524 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0030137 |
COPI-coated vesicle |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q63524 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q63524 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q6FHT8 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031410 |
cytoplasmic vesicle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016192 |
vesicle-mediated transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015031 |
protein transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0033116 |
endoplasmic reticulum-Golgi intermediate compartment membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030659 |
cytoplasmic vesicle membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030663 |
COPI-coated vesicle membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032580 |
Golgi cisterna membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 Jerome-Majewska, LA et al. (2010) The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta. Dev. Biol. 341 154-66 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
c
e
- GO:0048598 ! embryonic morphogenesis
- GO:0001892 ! embryonic placenta development
- GO:0033116 ! endoplasmic reticulum-Golgi intermediate compartment membrane
- GO:0005793 ! endoplasmic reticulum-Golgi intermediate compartment
- GO:0005783 ! endoplasmic reticulum
- GO:0005789 ! endoplasmic reticulum membrane
- GO:0006888 ! endoplasmic reticulum to Golgi vesicle-mediated transport
- Euarchontoglires
- Eukaryota
- Euteleostomi
- Eutheria
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