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MOUSE:TKT

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Tkt
Protein Name(s) Transketolase

TK P68

External Links
UniProt P40142
EMBL U05809
AK002627
AK012794
AK030446
AK140965
AK144146
AK146157
AK150139
AK150769
AK150844
AK150856
AK152460
AK159922
AK167084
BC055336
U90889
AF195533
CCDS CCDS26894.1
RefSeq NP_033414.1
UniGene Mm.290692
ProteinModelPortal P40142
SMR P40142
IntAct P40142
MINT MINT-1855010
PhosphoSite P40142
REPRODUCTION-2DPAGE P40142
SWISS-2DPAGE P40142
MaxQB P40142
PaxDb P40142
PRIDE P40142
Ensembl ENSMUST00000022529
GeneID 21881
KEGG mmu:21881
UCSC uc007svc.1
CTD 7086
MGI MGI:105992
eggNOG COG0021
GeneTree ENSGT00390000005240
HOGENOM HOG000243868
HOVERGEN HBG004036
InParanoid P40142
KO K00615
OMA ESNINFC
OrthoDB EOG72RMXF
PhylomeDB P40142
TreeFam TF313097
Reactome REACT_239811
REACT_246505
ChiTaRS Tkt
NextBio 301390
PRO PR:P40142
Proteomes UP000000589
Bgee P40142
CleanEx MM_TKT
ExpressionAtlas P40142
Genevestigator P40142
GO GO:0070062
GO:0005634
GO:0048037
GO:0046872
GO:0004802
GO:0046166
GO:0040008
Gene3D 3.40.50.920
3.40.50.970
InterPro IPR029061
IPR009014
IPR005475
IPR020826
IPR005476
IPR005474
Pfam PF02779
PF02780
PF00456
SMART SM00861
SUPFAM SSF52518
SSF52922
PROSITE PS00801
PS00802

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0043209

myelin sheath

PMID:17634366[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(CL:0000128)

Seeded From UniProt

complete

enables

GO:0048037

cofactor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P29401

F

Seeded From UniProt

complete

enables

GO:0048029

monosaccharide binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621036

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0046390

ribose phosphate biosynthetic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621036

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0046166

glyceraldehyde-3-phosphate biosynthetic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P29401

P

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621036

C

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P29401

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0040008

regulation of growth

PMID:12167708[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2671068

P

Seeded From UniProt

complete

enables

GO:0030976

thiamine pyrophosphate binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621036

F

Seeded From UniProt

complete

enables

GO:0030246

carbohydrate binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621036

F

Seeded From UniProt

complete

part_of

GO:0016607

nuclear speck

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P29401

C

Seeded From UniProt

complete

part_of

GO:0016604

nuclear body

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P29401

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0009052

pentose-phosphate shunt, non-oxidative branch

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621036

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006098

pentose-phosphate shunt

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621036

P

Seeded From UniProt

complete

part_of

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621036

C

Seeded From UniProt

complete

part_of

GO:0005777

peroxisome

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621036

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P29401

C

Seeded From UniProt

complete

enables

GO:0004802

transketolase activity

PMID:12167708[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004802

transketolase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P29401

F

Seeded From UniProt

complete

enables

GO:0004802

transketolase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621036

F

Seeded From UniProt

complete

enables

GO:0000287

magnesium ion binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621036

F

Seeded From UniProt

complete

enables

GO:0048037

cofactor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P29401
ensembl:ENSP00000391481

F

Seeded From UniProt

complete

involved_in

GO:0046166

glyceraldehyde-3-phosphate biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P29401
ensembl:ENSP00000391481

P

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P29401
ensembl:ENSP00000391481

F

Seeded From UniProt

complete

part_of

GO:0016607

nuclear speck

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P29401
ensembl:ENSP00000391481

C

Seeded From UniProt

complete

part_of

GO:0016604

nuclear body

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P29401
ensembl:ENSP00000391481

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P29401
ensembl:ENSP00000391481

C

Seeded From UniProt

complete

enables

GO:0004802

transketolase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P29401
ensembl:ENSP00000391481

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009014

F

Seeded From UniProt

complete

enables

GO:0004802

transketolase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.2.1.1

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Werner, HB et al. (2007) Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. J. Neurosci. 27 7717-30 PubMed GONUTS page
  2. 2.0 2.1 Xu, ZP et al. (2002) Transketolase haploinsufficiency reduces adipose tissue and female fertility in mice. Mol. Cell. Biol. 22 6142-7 PubMed GONUTS page