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MOUSE:TKN4

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Tac4 (ECO:0000312 with MGI:MGI:1931130)
Protein Name(s) Tachykinin-4

Preprotachykinin-C PPT-C Hemokinin HK1 Hemokinin-1 Hemokinin-I HK-I

External Links
UniProt Q99N14
EMBL AF235035
AF515827
AL627222
BC119426
CCDS CCDS25274.1
RefSeq NP_444323.1
UniGene Mm.40085
STRING 10090.ENSMUSP00000021242
PRIDE Q99N14
Ensembl ENSMUST00000021242
GeneID 93670
KEGG mmu:93670
UCSC uc007lac.1
CTD 255061
MGI MGI:1931130
eggNOG NOG43589
GeneTree ENSGT00390000015220
HOGENOM HOG000154596
HOVERGEN HBG097570
InParanoid Q99N14
KO K05241
OMA YQLGRIV
OrthoDB EOG7NSB4F
PhylomeDB Q99N14
TreeFam TF338519
NextBio 351366
PRO PR:Q99N14
Proteomes UP000000589
Bgee Q99N14
CleanEx MM_TAC4
Genevestigator Q99N14
GO GO:0005576
GO:0042629
GO:0005102
GO:0043303
GO:0046878
GO:0008217
GO:0007217
InterPro IPR013055
PROSITE PS00267

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0007217

tachykinin receptor signaling pathway

PMID:12716968[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0048018

receptor ligand activity

PMID:12716968[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0007204

positive regulation of cytosolic calcium ion concentration

PMID:12716968[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0031837

substance K receptor binding

PMID:12716968[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P21452

F

Seeded From UniProt

complete

enables

GO:0031835

substance P receptor binding

PMID:12716968[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P25103

F

Seeded From UniProt

complete

enables

GO:0031835

substance P receptor binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1931130
PANTHER:PTN002257995
RGD:3807
UniProtKB:Q86UU9

F

Seeded From UniProt

complete

involved_in

GO:0007217

tachykinin receptor signaling pathway

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1931130
PANTHER:PTN002257995
UniProtKB:Q86UU9

P

Seeded From UniProt

complete

involved_in

GO:0007204

positive regulation of cytosolic calcium ion concentration

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1931130
PANTHER:PTN002257995
RGD:3807
UniProtKB:P20366
UniProtKB:Q86UU9

P

Seeded From UniProt

complete

involved_in

GO:0006954

inflammatory response

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98474
PANTHER:PTN002257995

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002257995
RGD:3807
UniProtKB:Q86UU9

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0046878

positive regulation of saliva secretion

PMID:11062498[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007217

tachykinin receptor signaling pathway

PMID:11062498[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005102

signaling receptor binding

PMID:11062498[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005623

cell

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0007204

C

Seeded From UniProt

complete

part_of

GO:0005623

cell

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0007204

C

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0048018

P

Seeded From UniProt

complete

part_of

GO:0042629

mast cell granule

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0043303

C

Seeded From UniProt

complete

involved_in

GO:0007217

tachykinin receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008216

P

Seeded From UniProt

complete

involved_in

GO:0008217

regulation of blood pressure

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0382

P

Seeded From UniProt

complete

involved_in

GO:0043303

mast cell degranulation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0467

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Page, NM et al. (2003) Characterization of the endokinins: human tachykinins with cardiovascular activity. Proc. Natl. Acad. Sci. U.S.A. 100 6245-50 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 3.2 Zhang, Y et al. (2000) Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis. Nat. Immunol. 1 392-7 PubMed GONUTS page