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MOUSE:TEKT4

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Tekt4
Protein Name(s) Tektin-4

Testicular microtubules-related protein 4

External Links
UniProt Q149S1
EMBL AY485267
AK005842
BC117510
BC117526
CCDS CCDS28519.1
RefSeq NP_082227.1
UniGene Mm.282330
BioGrid 214969
PhosphoSite Q149S1
REPRODUCTION-2DPAGE Q149S1
MaxQB Q149S1
PaxDb Q149S1
PRIDE Q149S1
Ensembl ENSMUST00000025002
GeneID 71840
KEGG mmu:71840
UCSC uc008baw.1
CTD 150483
MGI MGI:1919090
eggNOG NOG251508
GeneTree ENSGT00390000016344
HOGENOM HOG000246943
HOVERGEN HBG056503
InParanoid Q149S1
KO K18631
OrthoDB EOG7HB58W
PhylomeDB Q149S1
TreeFam TF320754
NextBio 334692
PRO PR:Q149S1
Proteomes UP000000589
Bgee Q149S1
CleanEx MM_TEKT4
Genevestigator Q149S1
GO GO:0005737
GO:0005874
GO:0031514
GO:0030030
GO:0080154
InterPro IPR000435
PRINTS PR00511

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0060474

positive regulation of sperm motility involved in capacitation

PMID:17244819[1]

ECO:0000315

P

Fig 6 shows that mutant TEKT4 sperm have decreased motility

complete
CACAO 6613

involved_in

GO:0060378

regulation of brood size

PMID:18951373[2]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:Q6X6Z7

P

Seeded From UniProt

complete

involved_in

GO:0060294

cilium movement involved in cell motility

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1919090
PANTHER:PTN000462267

P

Seeded From UniProt

complete

involved_in

GO:0060271

cilium assembly

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1918312
PANTHER:PTN000462267
ZFIN:ZDB-GENE-080130-2

P

Seeded From UniProt

complete

part_of

GO:0036126

sperm flagellum

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1917676
MGI:MGI:1919090
PANTHER:PTN000462268
RGD:1310582

C

Seeded From UniProt

complete

involved_in

GO:0030317

flagellated sperm motility

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1346335
MGI:MGI:1918312
PANTHER:PTN000462268

P

Seeded From UniProt

complete

part_of

GO:0097228

sperm principal piece

PMID:17244819[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000019)

Seeded From UniProt

complete

part_of

GO:0097225

sperm midpiece

PMID:17244819[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000019)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0060294

cilium movement involved in cell motility

PMID:17244819[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3790114

P

occurs_in:(CL:0000019)

Seeded From UniProt

complete

part_of

GO:0036126

sperm flagellum

PMID:18247331[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003674

molecular_function

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0031514

motile cilium

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0282
UniProtKB-SubCell:SL-0117

C

Seeded From UniProt

complete

involved_in

GO:0030030

cell projection organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0970

P

Seeded From UniProt

complete

part_of

GO:0005929

cilium

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0969

C

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Roy, A et al. (2007) Absence of tektin 4 causes asthenozoospermia and subfertility in male mice. FASEB J. 21 1013-25 PubMed GONUTS page
  2. Roy, A et al. (2009) Tektin 3 is required for progressive sperm motility in mice. Mol. Reprod. Dev. 76 453-9 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  4. Guan, J & Yuan, L (2008) A heat-shock protein 40, DNAJB13, is an axoneme-associated component in mouse spermatozoa. Mol. Reprod. Dev. 75 1379-86 PubMed GONUTS page