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MOUSE:TECT2
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Tctn2 (synonyms: Tect2) | |
| Protein Name(s) | Tectonic-2 | |
| External Links | ||
| UniProt | Q2MV57 | |
| EMBL | DQ278869 AK014476 AK031829 BC058375 | |
| RefSeq | NP_080762.1 | |
| UniGene | Mm.1158 | |
| BioGrid | 212577 | |
| IntAct | Q2MV57 | |
| PhosphoSite | Q2MV57 | |
| MaxQB | Q2MV57 | |
| PRIDE | Q2MV57 | |
| GeneID | 67978 | |
| KEGG | mmu:67978 | |
| UCSC | uc008zqg.2 | |
| CTD | 79867 | |
| MGI | MGI:1915228 | |
| eggNOG | NOG76248 | |
| HOGENOM | HOG000013148 | |
| HOVERGEN | HBG083562 | |
| InParanoid | Q2MV57 | |
| PhylomeDB | Q2MV57 | |
| ChiTaRS | Tctn2 | |
| NextBio | 326118 | |
| PRO | PR:Q2MV57 | |
| Proteomes | UP000000589 | |
| Bgee | Q2MV57 | |
| CleanEx | MM_TCTN2 | |
| Genevestigator | Q2MV57 | |
| GO | GO:0005737 GO:0005856 GO:0016021 GO:0036038 GO:0042384 GO:0060271 GO:0007224 | |
| InterPro | IPR011677 | |
| Pfam | PF07773 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0060271 |
cilium assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1904491 |
protein localization to ciliary transition zone |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
transports_or_maintains_localization_of:(UniProtKB:Q9D3H0) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0060271 |
cilium assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0036038 |
MKS complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0036038 |
MKS complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007224 |
smoothened signaling pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0036038 |
MKS complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030030 |
cell projection organization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042995 |
cell projection |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
Contributes to |
GO:0001843 |
neural tube closure |
ECO:0000315 |
P |
in figure 6A. neural tube closure defects and exencephaly is showed. this was done by creating Tctn2 null mice with a mixed background of 129/Bl6. presenting Tctn2 mutants |
complete | ||||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Garcia-Gonzalo, FR et al. (2011) A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition. Nat. Genet. 43 776-84 PubMed GONUTS page
- ↑ Li, C et al. (2016) MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone. PLoS Biol. 14 e1002416 PubMed GONUTS page
- ↑ 3.0 3.1 Sang, L et al. (2011) Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell 145 513-28 PubMed GONUTS page
- ↑ 4.0 4.1 Chih, B et al. (2012) A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain. Nat. Cell Biol. 14 61-72 PubMed GONUTS page
- ↑ Skrabanek, P () Cervical cancer screening: the time for reappraisal. Can J Public Health 79 86-9 PubMed GONUTS page
