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MOUSE:TDRD6

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Tdrd6
Protein Name(s) Tudor domain-containing protein 6
External Links
UniProt P61407
EMBL AB097085
CCDS CCDS28797.1
RefSeq NP_940810.2
UniGene Mm.329058
ProteinModelPortal P61407
SMR P61407
STRING 10090.ENSMUSP00000131277
iPTMnet P61407
PhosphoSitePlus P61407
PaxDb P61407
PRIDE P61407
GeneID 210510
KEGG mmu:210510
CTD 221400
MGI MGI:2679727
eggNOG KOG2039
ENOG4110W7C
HOGENOM HOG000154540
HOVERGEN HBG059095
InParanoid P61407
KO K18405
PhylomeDB P61407
Reactome [www.reactome.org/content/detail/R-MMU-5601884 R-MMU-5601884]
PRO PR:P61407
Proteomes UP000000589
CleanEx MM_TDRD6
GO GO:0033391
GO:0005737
GO:0005829
GO:0005783
GO:0030529
GO:0043186
GO:0007281
GO:0007275
GO:0034587
GO:0007283
InterPro IPR002999
Pfam PF00567
SMART SM00333
PROSITE PS50304

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0000387

spliceosomal snRNP assembly

PMID:28263986[1]

ECO:0000315

P

Fig 3, human Tdrd6.

complete
CACAO 12787

part_of

GO:0033391

chromatoid body

PMID:19345099[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0007283

spermatogenesis

PMID:19345099[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:19345099[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:1990904

ribonucleoprotein complex

PMID:17141210[3]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(EMAPA:17972)

Seeded From UniProt

complete

part_of

GO:0043186

P granule

PMID:17141210[3]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000039)

Seeded From UniProt

complete

part_of

GO:0043186

P granule

PMID:16093322[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007281

germ cell development

PMID:17141210[3]

ECO:0000314

direct assay evidence used in manual assertion

P

results_in_development_of:(CL:0000017)

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

PMID:17662146[5]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(EMAPA:17972)

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-MMU-5629239
Reactome:R-MMU-5615685
Reactome:R-MMU-5605344

ECO:0000304

author statement supported by traceable reference used in manual assertion



C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

involved_in

GO:0007283

spermatogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0744

P

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Akpınar, M et al. (2017) TDRD6 mediates early steps of spliceosome maturation in primary spermatocytes. PLoS Genet. 13 e1006660 PubMed GONUTS page
  2. 2.0 2.1 2.2 Vasileva, A et al. (2009) Tdrd6 is required for spermiogenesis, chromatoid body architecture, and regulation of miRNA expression. Curr. Biol. 19 630-9 PubMed GONUTS page
  3. 3.0 3.1 3.2 Hosokawa, M et al. (2007) Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice. Dev. Biol. 301 38-52 PubMed GONUTS page
  4. Pan, J et al. (2005) RNF17, a component of the mammalian germ cell nuage, is essential for spermiogenesis. Development 132 4029-39 PubMed GONUTS page
  5. Choi, E et al. (2007) Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library. BMC Genomics 8 256 PubMed GONUTS page