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MOUSE:TBC15

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Tbc1d15
Protein Name(s) TBC1 domain family member 15

GTPase-activating protein RAB7 GAP for RAB7 Rab7-GAP

External Links
UniProt Q9CXF4
EMBL AK014477
AK078875
AK147085
CCDS CCDS24176.1
RefSeq NP_079982.3
UniGene Mm.22252
ProteinModelPortal Q9CXF4
SMR Q9CXF4
BioGrid 211646
IntAct Q9CXF4
MINT MINT-1726912
PhosphoSite Q9CXF4
MaxQB Q9CXF4
PaxDb Q9CXF4
PRIDE Q9CXF4
Ensembl ENSMUST00000020339
GeneID 66687
KEGG mmu:66687
UCSC uc007hax.2
CTD 64786
MGI MGI:1913937
eggNOG COG5210
GeneTree ENSGT00550000074386
HOGENOM HOG000012710
HOVERGEN HBG057668
InParanoid Q9CXF4
OMA VEDVLCK
OrthoDB EOG7HTHHR
PhylomeDB Q9CXF4
TreeFam TF314296
ChiTaRS Tbc1d15
NextBio 322377
PRO PR:Q9CXF4
Proteomes UP000000589
Bgee Q9CXF4
CleanEx MM_TBC1D15
ExpressionAtlas Q9CXF4
Genevestigator Q9CXF4
GO GO:0005737
GO:0005576
GO:0070062
GO:0005739
GO:0005097
GO:0032851
GO:0032313
InterPro IPR021935
IPR000195
Pfam PF12068
PF00566
SMART SM00164
SUPFAM SSF47923
PROSITE PS50086

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0043087

regulation of GTPase activity

PMID:16055087[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:16055087[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005096

GTPase activator activity

PMID:16055087[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0090630

activation of GTPase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000537561
SGD:S000005237
dictyBase:DDB_G0276119
dictyBase:DDB_G0280955

P

Seeded From UniProt

complete

enables

GO:0017137

Rab GTPase binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0031233
FB:FBgn0038129
FB:FBgn0261261
FB:FBgn0262740
MGI:MGI:107320
MGI:MGI:2385326
PANTHER:PTN000537561
UniProtKB:O43147
UniProtKB:O60447
UniProtKB:Q2NKQ1
UniProtKB:Q5R372
UniProtKB:Q8IYX1
UniProtKB:Q92738
UniProtKB:Q96CN4
UniProtKB:Q96HU1
UniProtKB:Q9Y2I9
UniProtKB:Q9Y3P9
WB:WBGene00008018
WB:WBGene00020572
dictyBase:DDB_G0269130
dictyBase:DDB_G0280955

F

Seeded From UniProt

complete

involved_in

GO:0006886

intracellular protein transport

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2385326
PANTHER:PTN000537561
SGD:S000003332

P

Seeded From UniProt

complete

enables

GO:0005096

GTPase activator activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0262740
MGI:MGI:1913937
MGI:MGI:2144695
MGI:MGI:2385326
PANTHER:PTN000537561
PomBase:SPAC6F6.08c
SGD:S000002393
SGD:S000003332
SGD:S000003580
SGD:S000004659
SGD:S000005237
SGD:S000005472
SGD:S000005596
SGD:S000006170
UniProtKB:O43147
UniProtKB:O60447
UniProtKB:Q2NKQ1
UniProtKB:Q3MII6
UniProtKB:Q4KMP7
UniProtKB:Q5R372
UniProtKB:Q8TBP0
UniProtKB:Q92738
UniProtKB:Q96CN4
UniProtKB:Q96HU1
UniProtKB:Q9BYX2
UniProtKB:Q9Y2I9
UniProtKB:Q9Y3P9
WB:WBGene00007167
WB:WBGene00022880
dictyBase:DDB_G0269130
dictyBase:DDB_G0276119
dictyBase:DDB_G0280955

F

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:14651853[3]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(EMAPA:16846)|part_of:(EMAPA:16894)|part_of:(EMAPA:17373)|part_of:(EMAPA:16105)

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

PMID:10714688[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005096

GTPase activator activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0343

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Zhang, XM et al. (2005) TBC domain family, member 15 is a novel mammalian Rab GTPase-activating protein with substrate preference for Rab7. Biochem. Biophys. Res. Commun. 335 154-61 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. Mootha, VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115 629-40 PubMed GONUTS page
  4. Apostolopoulos, J et al. (2000) Ly6d-L, a cell surface ligand for mouse Ly6d. Immunity 12 223-32 PubMed GONUTS page