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MOUSE:STRC

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Strc
Protein Name(s) Stereocilin
External Links
UniProt Q8VIM6
EMBL AF375593
AL845466
CCDS CCDS16641.1
RefSeq NP_536707.2
XP_006498797.1
UniGene Mm.467475
ProteinModelPortal Q8VIM6
STRING 10090.ENSMUSP00000039378
PhosphoSite Q8VIM6
PaxDb Q8VIM6
PRIDE Q8VIM6
Ensembl ENSMUST00000038389
GeneID 140476
KEGG mmu:140476
UCSC uc008lyw.1
CTD 161497
MGI MGI:2153816
eggNOG NOG29484
GeneTree ENSGT00530000063809
HOGENOM HOG000231838
HOVERGEN HBG079223
InParanoid Q8VIM6
OMA MAFLSPE
OrthoDB EOG79GT8H
TreeFam TF330914
NextBio 369768
PRO PR:Q8VIM6
Proteomes UP000000589
Bgee Q8VIM6
CleanEx MM_STRC
ExpressionAtlas Q8VIM6
Genevestigator Q8VIM6
GO GO:0009986
GO:0060091
GO:0032420
GO:0032426
GO:0060088
GO:0050910
GO:0007605
InterPro IPR026061
IPR026664
PANTHER PTHR23412
PTHR23412:SF16

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0060091

kinocilium

PMID:21165971[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0060088

auditory receptor cell stereocilium organization

PMID:21165971[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0032426

stereocilium tip

PMID:21165971[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0060091

kinocilium

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2153816
PANTHER:PTN001158356

C

Seeded From UniProt

complete

part_of

GO:0032426

stereocilium tip

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2153816
PANTHER:PTN001158356

C

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001517636
RGD:69333

C

Seeded From UniProt

complete

involved_in

GO:0007160

cell-matrix adhesion

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2149209
PANTHER:PTN001517636

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0060088

auditory receptor cell stereocilium organization

PMID:18849963[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3818633

P

occurs_in:(CL:0000601)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0050910

detection of mechanical stimulus involved in sensory perception of sound

PMID:18849963[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3818633

P

Seeded From UniProt

complete

part_of

GO:0032426

stereocilium tip

PMID:24920589[4]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(CL:0000601)
  • part_of:(EMAPA:17597)

Seeded From UniProt

complete

part_of

GO:0032426

stereocilium tip

PMID:18849963[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007605

sensory perception of sound

PMID:11687802[5]

ECO:0000266

sequence orthology evidence used in manual assertion

EMBL:AF375594

P

Seeded From UniProt

complete

enables

GO:0003674

molecular_function

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

part_of

GO:0005929

cilium

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0969

C

Seeded From UniProt

complete

involved_in

GO:0007605

sensory perception of sound

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1009

P

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0310

C

Seeded From UniProt

complete

part_of

GO:0032420

stereocilium

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0302

C

Seeded From UniProt

complete

part_of

GO:0060091

kinocilium

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0460

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Verpy, E et al. (2011) Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane. J. Comp. Neurol. 519 194-210 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 3.2 Verpy, E et al. (2008) Stereocilin-deficient mice reveal the origin of cochlear waveform distortions. Nature 456 255-8 PubMed GONUTS page
  4. Kamiya, K et al. (2014) An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells. Proc. Natl. Acad. Sci. U.S.A. 111 9307-12 PubMed GONUTS page
  5. Verpy, E et al. (2001) Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus. Nat. Genet. 29 345-9 PubMed GONUTS page