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MOUSE:SPB5

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Serpinb5 (synonyms: Pi5, Spi5, Spi7)
Protein Name(s) Serpin B5

Maspin Peptidase inhibitor 5 PI-5

External Links
UniProt P70124
EMBL U54705
AK136532
AK145220
CH466520
CH466520
BC005434
CCDS CCDS35684.1
RefSeq NP_033283.1
XP_006529353.1
XP_006529354.1
UniGene Mm.268618
ProteinModelPortal P70124
SMR P70124
BioGrid 203447
STRING 10090.ENSMUSP00000108350
MEROPS I04.980
PhosphoSite P70124
MaxQB P70124
PaxDb P70124
PRIDE P70124
Ensembl ENSMUST00000086701
ENSMUST00000112729
ENSMUST00000112730
GeneID 20724
KEGG mmu:20724
UCSC uc007cha.1
CTD 5268
MGI MGI:109579
eggNOG COG4826
GeneTree ENSGT00760000118789
HOGENOM HOG000238519
HOVERGEN HBG005957
InParanoid P70124
KO K10139
OMA MMSMEAT
OrthoDB EOG7327PB
PhylomeDB P70124
TreeFam TF352619
ChiTaRS Serpinb5
NextBio 299325
PRO PR:P70124
Proteomes UP000000589
Bgee P70124
Genevestigator P70124
GO GO:0005737
GO:0005615
GO:0070062
GO:0004867
GO:0030198
GO:0002009
GO:0010951
GO:0060512
GO:0050678
GO:0030162
InterPro IPR000240
IPR023795
IPR023796
IPR000215
PANTHER PTHR11461
Pfam PF00079
PRINTS PR00676
SMART SM00093
SUPFAM SSF56574
PROSITE PS00284

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0010951

negative regulation of endopeptidase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0028988
FB:FBgn0265137
PANTHER:PTN000156123
RGD:3249
UniProtKB:P05121
UniProtKB:P29508
UniProtKB:P35237
UniProtKB:P50452
UniProtKB:P50453
UniProtKB:Q9UIV8

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0002930
FB:FBgn0015586
FB:FBgn0028986
FB:FBgn0031973
FB:FBgn0262057
FB:FBgn0265137
MGI:MGI:108080
MGI:MGI:1915304
MGI:MGI:87963
MGI:MGI:88278
MGI:MGI:894696
PANTHER:PTN000156123
RGD:1306692
RGD:1307404
RGD:2069
RGD:3249
RGD:3326
RGD:3747
RGD:3748
RGD:619833
RGD:631369
RGD:735225
UniProtKB:P01008
UniProtKB:P01009
UniProtKB:P01011
UniProtKB:P01019
UniProtKB:P05121
UniProtKB:P05154
UniProtKB:P08697
UniProtKB:P50453
UniProtKB:Q90935
UniProtKB:Q99574
UniProtKB:Q9TTE1

C

Seeded From UniProt

complete

enables

GO:0004867

serine-type endopeptidase inhibitor activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0002930
FB:FBgn0028983
FB:FBgn0028988
FB:FBgn0028990
FB:FBgn0265137
MGI:MGI:101780
MGI:MGI:106603
MGI:MGI:1277952
MGI:MGI:2445361
MGI:MGI:2683293
MGI:MGI:891970
MGI:MGI:894696
MGI:MGI:97608
PANTHER:PTN000156123
RGD:1306692
RGD:1307404
RGD:3249
RGD:3326
RGD:3748
RGD:619817
RGD:619896
RGD:619897
UniProtKB:P01009
UniProtKB:P01012
UniProtKB:P05121
UniProtKB:P05154
UniProtKB:P05155
UniProtKB:P07093
UniProtKB:P08697
UniProtKB:P35237
UniProtKB:P48594
UniProtKB:P50452
UniProtKB:P50453
UniProtKB:Q3ZEJ6
UniProtKB:Q86WD7
UniProtKB:Q90935
UniProtKB:Q96P63
UniProtKB:Q99574
UniProtKB:Q9TTE1
UniProtKB:Q9UIV8
WB:WBGene00005643

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0060512

prostate gland morphogenesis

PMID:18593913[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3040188

P

has_participant:(EMAPA:32290)

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0050678

regulation of epithelial cell proliferation

PMID:18593913[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3040188

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030198

extracellular matrix organization

PMID:18593913[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3040188

P

occurs_in:(EMAPA:19287)

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:18593913[2]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(EMAPA:32290)
  • part_of:(CL:0000066)|part_of:(EMAPA:35713)
  • part_of:(CL:0000192)

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P36952

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0002009

morphogenesis of an epithelium

PMID:18593913[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3040188

P

has_participant:(EMAPA:32290)

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P36952
ensembl:ENSP00000372221

C

Seeded From UniProt

complete

enables

GO:0004867

serine-type endopeptidase inhibitor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000240
InterPro:IPR033836

F

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000215

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0112

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Shao, LJ et al. (2008) Haploinsufficiency of the maspin tumor suppressor gene leads to hyperplastic lesions in prostate. Cancer Res. 68 5143-51 PubMed GONUTS page