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MOUSE:SIA8B

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) St8sia2 (synonyms: Siat8b, Stx)
Protein Name(s) Alpha-2,8-sialyltransferase 8B

Polysialic acid synthase Sialyltransferase 8B SIAT8-B Sialyltransferase St8Sia II ST8SiaII Sialyltransferase X STX

External Links
UniProt O35696
EMBL X99646
X99647
X99648
X99651
X99649
X99650
X83562
BC096546
CH466543
CCDS CCDS21365.1
PIR I48686
RefSeq NP_033207.2
UniGene Mm.4954
ProteinModelPortal O35696
SMR O35696
DIP DIP-59528N
STRING 10090.ENSMUSP00000026896
CAZy GT29
PhosphoSite O35696
MaxQB O35696
PRIDE O35696
Ensembl ENSMUST00000026896
GeneID 20450
KEGG mmu:20450
UCSC uc009hwe.2
CTD 8128
MGI MGI:106020
eggNOG NOG324948
GeneTree ENSGT00550000074407
HOGENOM HOG000232070
HOVERGEN HBG056466
InParanoid O35696
KO K06612
OMA IHYVFDR
OrthoDB EOG7VQJD1
TreeFam TF352820
Reactome REACT_198565
REACT_202500
REACT_236183
UniPathway UPA00378
NextBio 298518
PRO PR:O35696
Proteomes UP000000589
Bgee O35696
Genevestigator O35696
GO GO:0005769
GO:0030173
GO:0055037
GO:0003828
GO:0001574
GO:0006491
GO:0097503
InterPro IPR001675
IPR012163
Pfam PF00777
PIRSF PIRSF005557

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0055037

recycling endosome

PMID:23303939[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0009311

oligosaccharide metabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q92186

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006491

N-glycan processing

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q92186

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006486

protein glycosylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q92186

P

Seeded From UniProt

complete

part_of

GO:0005769

early endosome

PMID:23303939[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003828

alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity

PMID:7875291[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003828

alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q92186

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001574

ganglioside biosynthetic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q92186

P

Seeded From UniProt

complete

involved_in

GO:0097503

sialylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008373

P

Seeded From UniProt

complete

involved_in

GO:0097503

sialylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003828

P

Seeded From UniProt

complete

involved_in

GO:0097503

sialylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0003828

P

Seeded From UniProt

complete

involved_in

GO:0097503

sialylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0003828

P

Seeded From UniProt

complete

involved_in

GO:0009311

oligosaccharide metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92186
ensembl:ENSP00000268164

P

Seeded From UniProt

complete

involved_in

GO:0006491

N-glycan processing

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92186
ensembl:ENSP00000268164

P

Seeded From UniProt

complete

involved_in

GO:0006486

protein glycosylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92186
ensembl:ENSP00000268164

P

Seeded From UniProt

complete

enables

GO:0003828

alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92186
ensembl:ENSP00000268164

F

Seeded From UniProt

complete

involved_in

GO:0001574

ganglioside biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92186
ensembl:ENSP00000268164

P

Seeded From UniProt

complete

involved_in

GO:0006486

protein glycosylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001675
InterPro:IPR012163

P

Seeded From UniProt

complete

enables

GO:0008373

sialyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001675
InterPro:IPR012163

F

Seeded From UniProt

complete

enables

GO:0016757

transferase activity, transferring glycosyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0328

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0000139

Golgi membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0134

C

Seeded From UniProt

complete

involved_in

GO:0006486

protein glycosylation

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00378

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Deane, EC et al. (2013) Enhanced recruitment of endosomal Na+/H+ exchanger NHE6 into Dendritic spines of hippocampal pyramidal neurons during NMDA receptor-dependent long-term potentiation. J. Neurosci. 33 595-610 PubMed GONUTS page
  2. Kojima, N et al. (1995) Enzymatic activity of a developmentally regulated member of the sialyltransferase family (STX): evidence for alpha 2,8-sialyltransferase activity toward N-linked oligosaccharides. FEBS Lett. 360 1-4 PubMed GONUTS page