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MOUSE:SC5AC

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Slc5a12 (synonyms: Smct2)
Protein Name(s) Sodium-coupled monocarboxylate transporter 2

Electroneutral sodium monocarboxylate cotransporter Low-affinity sodium-lactate cotransporter Solute carrier family 5 member 12

External Links
UniProt Q49B93
EMBL AY964639
AF529222
AK144004
AK165419
AL732495
BX005257
AL732495
BX005257
BX005257
AL732495
BX005257
AL732495
BC121791
CCDS CCDS16512.1
CCDS50656.1
RefSeq NP_001003915.1
NP_001171095.1
UniGene Mm.277148
ProteinModelPortal Q49B93
SMR Q49B93
STRING 10090.ENSMUSP00000047340
PhosphoSite Q49B93
MaxQB Q49B93
PaxDb Q49B93
PRIDE Q49B93
DNASU 241612
Ensembl ENSMUST00000045972
ENSMUST00000111026
GeneID 241612
KEGG mmu:241612
UCSC uc008lmw.2
uc008lmx.2
CTD 159963
MGI MGI:2138890
eggNOG COG0591
GeneTree ENSGT00760000118955
HOGENOM HOG000261662
HOVERGEN HBG057280
InParanoid Q49B93
KO K14388
OMA GVLCTSM
OrthoDB EOG70PBX7
PhylomeDB Q49B93
TreeFam TF316728
ChiTaRS Slc5a12
NextBio 385076
PRO PR:Q49B93
Proteomes UP000000589
Bgee Q49B93
ExpressionAtlas Q49B93
Genevestigator Q49B93
GO GO:0016324
GO:0070062
GO:0016021
GO:0015293
GO:0006814
InterPro IPR001734
IPR019900
PANTHER PTHR11819
Pfam PF00474
TIGRFAMs TIGR00813
PROSITE PS50283

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0015129

lactate transmembrane transporter activity

PMID:16104846[1]

ECO:0000314

F

Figure 2 shows the transporters substrate specificity to monocarboxylates.

complete
CACAO 7209

enables

GO:0015129

lactate transmembrane transporter activity

PMID:16104846[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0015129

lactate transmembrane transporter activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2138890
PANTHER:PTN000213568

F

Seeded From UniProt

complete

involved_in

GO:0035873

lactate transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015129

P

Seeded From UniProt

complete

involved_in

GO:0035873

lactate transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015129

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001734

C

Seeded From UniProt

complete

enables

GO:0022857

transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001734

F

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001734

P

Seeded From UniProt

complete

enables

GO:0015293

symporter activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0769

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0006814

sodium ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0739

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0015

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Srinivas, SR et al. (2005) Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2). Biochem. J. 392 655-64 PubMed GONUTS page
  2. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page