GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
MOUSE:SC5AC
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Slc5a12 (synonyms: Smct2) | |
| Protein Name(s) | Sodium-coupled monocarboxylate transporter 2
Electroneutral sodium monocarboxylate cotransporter Low-affinity sodium-lactate cotransporter Solute carrier family 5 member 12 | |
| External Links | ||
| UniProt | Q49B93 | |
| EMBL | AY964639 AF529222 AK144004 AK165419 AL732495 BX005257 AL732495 BX005257 BX005257 AL732495 BX005257 AL732495 BC121791 | |
| CCDS | CCDS16512.1 CCDS50656.1 | |
| RefSeq | NP_001003915.1 NP_001171095.1 | |
| UniGene | Mm.277148 | |
| ProteinModelPortal | Q49B93 | |
| SMR | Q49B93 | |
| STRING | 10090.ENSMUSP00000047340 | |
| PhosphoSite | Q49B93 | |
| MaxQB | Q49B93 | |
| PaxDb | Q49B93 | |
| PRIDE | Q49B93 | |
| DNASU | 241612 | |
| Ensembl | ENSMUST00000045972 ENSMUST00000111026 | |
| GeneID | 241612 | |
| KEGG | mmu:241612 | |
| UCSC | uc008lmw.2 uc008lmx.2 | |
| CTD | 159963 | |
| MGI | MGI:2138890 | |
| eggNOG | COG0591 | |
| GeneTree | ENSGT00760000118955 | |
| HOGENOM | HOG000261662 | |
| HOVERGEN | HBG057280 | |
| InParanoid | Q49B93 | |
| KO | K14388 | |
| OMA | GVLCTSM | |
| OrthoDB | EOG70PBX7 | |
| PhylomeDB | Q49B93 | |
| TreeFam | TF316728 | |
| ChiTaRS | Slc5a12 | |
| NextBio | 385076 | |
| PRO | PR:Q49B93 | |
| Proteomes | UP000000589 | |
| Bgee | Q49B93 | |
| ExpressionAtlas | Q49B93 | |
| Genevestigator | Q49B93 | |
| GO | GO:0016324 GO:0070062 GO:0016021 GO:0015293 GO:0006814 | |
| InterPro | IPR001734 IPR019900 | |
| PANTHER | PTHR11819 | |
| Pfam | PF00474 | |
| TIGRFAMs | TIGR00813 | |
| PROSITE | PS50283 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0015129 |
lactate transmembrane transporter activity |
ECO:0000314 |
F |
Figure 2 shows the transporters substrate specificity to monocarboxylates. |
complete | |||||
|
enables |
GO:0015129 |
lactate transmembrane transporter activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015129 |
lactate transmembrane transporter activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2138890 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035873 |
lactate transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015129 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035873 |
lactate transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015129 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0022857 |
transmembrane transporter activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055085 |
transmembrane transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015293 |
symporter activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006811 |
ion transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006814 |
sodium ion transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016324 |
apical plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Srinivas, SR et al. (2005) Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2). Biochem. J. 392 655-64 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page