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MOUSE:RIT1

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Rit1 (synonyms: Rit)
Protein Name(s) GTP-binding protein Rit1

Ras-like protein expressed in many tissues Ras-like without CAAX protein 1

External Links
UniProt P70426
EMBL U71205
AK005357
AK014126
BC012694
CCDS CCDS17484.1
RefSeq NP_033095.1
XP_006501223.1
UniGene Mm.4009
ProteinModelPortal P70426
SMR P70426
BioGrid 202897
STRING 10090.ENSMUSP00000029692
iPTMnet P70426
PhosphoSite P70426
MaxQB P70426
PaxDb P70426
PRIDE P70426
Ensembl ENSMUST00000029692
GeneID 19769
UCSC uc008pwh.2
CTD 6016
MGI MGI:108053
eggNOG KOG0395
COG1100
GeneTree ENSGT00780000121857
HOGENOM HOG000233973
HOVERGEN HBG009351
InParanoid P70426
OMA KSSVWKR
OrthoDB EOG7QVM41
PhylomeDB P70426
TreeFam TF315072
NextBio 297224
PRO PR:P70426
Proteomes UP000000589
Bgee P70426
CleanEx MM_RIT1
ExpressionAtlas P70426
Genevisible P70426
GO GO:0005622
GO:0005886
GO:0005525
GO:0007265
Gene3D 3.40.50.300
InterPro IPR027417
IPR005225
IPR001806
IPR020849
PANTHER PTHR24070
Pfam PF00071
SMART SM00173
SUPFAM SSF52540
TIGRFAMs TIGR00231
PROSITE PS51421

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

acts_upstream_of_or_within

GO:0007265

Ras protein signal transduction

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q92963

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:8824319[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

PMID:8824319[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q92963

F

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q92963

F

Seeded From UniProt

complete

GO:0000302

response to reactive oxygen species

PMID:23123784[2]

ECO:0000314

P

Figure 2. Hippocampal neurons isolated from WT or Syn(CA)Rit Pi mouse pups were treated or untreated with H2O2 for 2h.

complete
CACAO 11684

involved_in

GO:0007265

Ras protein signal transduction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92963
ensembl:ENSP00000357305

P

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92963
ensembl:ENSP00000357305

F

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92963
ensembl:ENSP00000357305

F

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001806

F

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001806
InterPro:IPR005225
InterPro:IPR020849

F

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020849

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020849

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0342

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Lee, CH et al. (1996) Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins. J. Neurosci. 16 6784-94 PubMed GONUTS page
  2. Cai, W et al. (2012) Rit GTPase regulates a p38 MAPK-dependent neuronal survival pathway. Neurosci. Lett. 531 125-30 PubMed GONUTS page