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MOUSE:Q99M68
Contents
Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
Gene Name(s) | Oprm1 (ECO:0000313 with MGI:MGI:97441) | |
Protein Name(s) | Mu-opioid receptor (ECO:0000313 with EMBL:AAK31600.1) | |
External Links | ||
UniProt | Q99M68 | |
EMBL | AY028944 | |
UniGene | Mm.439715 | |
ProteinModelPortal | Q99M68 | |
BindingDB | Q99M68 | |
MGI | MGI:97441 | |
Bgee | Q99M68 | |
ExpressionAtlas | Q99M68 | |
Genevestigator | Q99M68 | |
GO | GO:0032839 GO:0032590 GO:0005925 GO:0016021 GO:0016020 GO:0045121 GO:0043204 GO:0042383 GO:0004979 GO:0038047 GO:0004985 GO:0005245 GO:0002438 GO:0007191 GO:0007193 GO:0031635 GO:0048149 GO:0033554 GO:0007626 GO:0007194 GO:0043951 GO:0051481 GO:0045019 GO:0061358 GO:0007200 GO:0032100 GO:0043950 GO:0007204 GO:0070374 GO:0045429 GO:0060079 GO:2000310 GO:0051930 GO:0042220 GO:0032094 GO:0070848 GO:0032496 GO:0042060 | |
InterPro | IPR000276 IPR017452 IPR001418 | |
Pfam | PF00001 | |
PRINTS | PR00237 PR00384 | |
PROSITE | PS50262 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:0035176 |
social behavior |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0038003 |
opioid receptor signaling pathway |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004985 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004985 |
opioid receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
GO:0035176 |
social behavior |
ECO:0000316 |
|
P |
Figure 6a shows that the mice who have already received social deficits through mutation are able to regain social behavior function through reducing the Oprm1 gene. This graph shows wild type mice having the highest amount of socialization time and the mutated mice with the most reduction of the Oprm1 gene regaining a lot of their lost socialization skills. |
complete | ||||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Samaco, RC et al. (2012) Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome. Nat. Genet. 44 206-11 PubMed GONUTS page