MOUSE:Q6IS31

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Pink1 (ECO:0000313 with EMBL:AAH69968.1, ECO:0000313 with MGI:MGI:1916193)
Protein Name(s)	Pink1 protein (ECO:0000313 with EMBL:AAH69968.1)
External Links
UniProt	Q6IS31
EMBL	BC069968
UniGene	Mm.18539
ProteinModelPortal	Q6IS31
MGI	MGI:1916193
HOVERGEN	HBG053601
ChiTaRS	Pink1
Genevestigator	Q6IS31
GO	GO:0005739 GO:0005524 GO:0016301 GO:0004674 GO:0033605 GO:0033603 GO:0032226
InterPro	IPR011009 IPR000719 IPR017441 IPR008271
Pfam	PF00069
SUPFAM	SSF56112
PROSITE	PS00107 PS50011 PS00108

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:1902412	regulation of mitotic cytokinesis	PMID:24681957	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0000422	autophagy of mitochondrion	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR040110	P		Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR008271	F		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR040110	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR017441	F		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR008271	P		Seeded From UniProt	complete
	GO:1902412	regulation of mitotic cytokinesis	PMID:24681957	ECO:0000315			P		Figure 3 demonstrates how cells without PINK1 protein are halted at G2/M phase of cell division and can no longer divide. Specifically in Figure 3b, it can be observed using double immunofluorescence, that cells lacking PINK1 did not divide even two hours after release from the nocodazole block. This illustrates that PINK1 is involved in regulation of cell division, because without it division halts.	complete CACAO 10036
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References

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