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MOUSE:PTCD1
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Ptcd1 | |
| Protein Name(s) | Pentatricopeptide repeat-containing protein 1, mitochondrial | |
| External Links | ||
| UniProt | Q8C2E4 | |
| EMBL | AK088764 AK171484 BC004766 BC083097 | |
| CCDS | CCDS19858.1 | |
| RefSeq | NP_598496.3 | |
| UniGene | Mm.277413 Mm.332840 Mm.474456 | |
| ProteinModelPortal | Q8C2E4 | |
| IntAct | Q8C2E4 | |
| MINT | Q8C2E4 | |
| STRING | 10090.ENSMUSP00000031628 | |
| PhosphoSitePlus | Q8C2E4 | |
| MaxQB | Q8C2E4 | |
| PaxDb | Q8C2E4 | |
| PRIDE | Q8C2E4 | |
| DNASU | 71799 | |
| Ensembl | ENSMUST00000031628 | |
| GeneID | 71799 | |
| KEGG | mmu:71799 | |
| UCSC | uc009amh.2 | |
| CTD | 26024 | |
| MGI | MGI:1919049 | |
| eggNOG | KOG4197 ENOG410Z7Z7 | |
| GeneTree | ENSGT00390000015597 | |
| HOGENOM | HOG000237315 | |
| HOVERGEN | HBG053748 | |
| InParanoid | Q8C2E4 | |
| KO | K17710 | |
| OMA | FRAYYKQ | |
| OrthoDB | EOG091G02E4 | |
| TreeFam | TF324792 | |
| PRO | PR:Q8C2E4 | |
| Proteomes | UP000000589 | |
| Bgee | ENSMUSG00000029624 | |
| CleanEx | MM_PTCD1 | |
| ExpressionAtlas | Q8C2E4 | |
| Genevisible | Q8C2E4 | |
| GO | GO:0005759 GO:0000049 GO:0042780 | |
| Gene3D | 1.25.40.10 | |
| InterPro | IPR002885 IPR011990 | |
| Pfam | PF13041 PF13812 | |
| TIGRFAMs | TIGR00756 | |
| PROSITE | PS51375 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0032543 |
mitochondrial translation |
ECO:0000315 |
P |
In this paper, they measured de novo mitochondrial protein synthesis of the 13 mtDNA-encoded respiratory complex subunits and showed a dramatic loss of translation in the Ptcd1 knockout mice compared to controls in both tissues (Figures 3A and S1A), indicating that PTCD1 is essential for mitochondrial protein synthesis. |
complete | |||||
|
involved_in |
GO:0042780 |
tRNA 3'-end processing |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005759 |
mitochondrial matrix |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000049 |
tRNA binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042780 |
tRNA 3'-end processing |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001165391 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005759 |
mitochondrial matrix |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001165391 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000049 |
tRNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001165391 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005759 |
mitochondrial matrix |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:1311473 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005759 |
mitochondrial matrix |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:A2VD13 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008033 |
tRNA processing |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005759 |
mitochondrial matrix |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Perks, KL et al. (2018) PTCD1 Is Required for 16S rRNA Maturation Complex Stability and Mitochondrial Ribosome Assembly. Cell Rep 23 127-142 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page