MOUSE:PON3

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Pon3
Protein Name(s)	Serum paraoxonase/lactonase 3
External Links
UniProt	Q62087
EMBL	L76193 AK088572 CH466533 BC099416
CCDS	CCDS19899.1
RefSeq	NP_766594.1
UniGene	Mm.9122
ProteinModelPortal	Q62087
SMR	Q62087
IntAct	Q62087
MINT	MINT-4108218
PhosphoSite	Q62087
MaxQB	Q62087
PaxDb	Q62087
PRIDE	Q62087
Ensembl	ENSMUST00000031773
GeneID	269823
KEGG	mmu:269823
UCSC	uc009awe.1
CTD	5446
MGI	MGI:106686
eggNOG	NOG68009
GeneTree	ENSGT00390000008932
HOGENOM	HOG000252960
HOVERGEN	HBG003604
InParanoid	Q62087
KO	K01045
OMA	QKYVYVA
PhylomeDB	Q62087
TreeFam	TF322436
NextBio	393049
PRO	PR:Q62087
Proteomes	UP000000589
Bgee	Q62087
CleanEx	MM_PON3
ExpressionAtlas	Q62087
Genevestigator	Q62087
GO	GO:0005615 GO:0070062 GO:0043231 GO:0018733 GO:0004063 GO:0004064 GO:0047856 GO:0046872 GO:0046226 GO:0010124
Gene3D	2.120.10.30
InterPro	IPR011042 IPR002640 IPR008364
Pfam	PF01731
PRINTS	PR01785 PR01787

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0032929	negative regulation of superoxide anion generation	PMID:22441669	ECO:0000314			P		Figure 4 C shows that PON3 diminishes mitochondrial superoxide formation when compared to PON3 knockout cells.	complete CACAO 9927
involved_in	GO:0032929	negative regulation of superoxide anion generation	PMID:22441669	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0009636	response to toxic substance		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103295 PANTHER:PTN000210195	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000210214 RGD:1302965	C		Seeded From UniProt	complete
enables	GO:0004064	arylesterase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103295 PANTHER:PTN000210195 RGD:1302965 UniProtKB:P27169 UniProtKB:Q15166	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0046395	carboxylic acid catabolic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15166	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0046226	coumarin catabolic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1302965	P		Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1302965	C		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15166	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0019439	aromatic compound catabolic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15166	P		Seeded From UniProt	complete
enables	GO:0018733	3,4-dihydrocoumarin hydrolase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1302965	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010124	phenylacetate catabolic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1302965	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1302965	C		Seeded From UniProt	complete
enables	GO:0004064	arylesterase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15166	F		Seeded From UniProt	complete
enables	GO:0004064	arylesterase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1302965	F		Seeded From UniProt	complete
involved_in	GO:0016311	dephosphorylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004063	P		Seeded From UniProt	complete
involved_in	GO:0046395	carboxylic acid catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15166 ensembl:ENSP00000265627	P		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15166 ensembl:ENSP00000265627	F		Seeded From UniProt	complete
involved_in	GO:0019439	aromatic compound catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15166 ensembl:ENSP00000265627	P		Seeded From UniProt	complete
enables	GO:0004064	arylesterase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15166 ensembl:ENSP00000265627	F		Seeded From UniProt	complete
involved_in	GO:0046226	coumarin catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q68FP2 ensembl:ENSRNOP00000012050	P		Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q68FP2 ensembl:ENSRNOP00000012050	C		Seeded From UniProt	complete
enables	GO:0018733	3,4-dihydrocoumarin hydrolase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q68FP2 ensembl:ENSRNOP00000012050	F		Seeded From UniProt	complete
involved_in	GO:0010124	phenylacetate catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q68FP2 ensembl:ENSRNOP00000012050	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q68FP2 ensembl:ENSRNOP00000012050	C		Seeded From UniProt	complete
enables	GO:0004064	arylesterase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q68FP2 ensembl:ENSRNOP00000012050	F		Seeded From UniProt	complete
enables	GO:0004064	arylesterase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002640 InterPro:IPR008364	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008364	C		Seeded From UniProt	complete
enables	GO:0004063	aryldialkylphosphatase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.1.8.1	F		Seeded From UniProt	complete
enables	GO:0004064	arylesterase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.1.1.2	F		Seeded From UniProt	complete
enables	GO:0102007	acyl-L-homoserine-lactone lactonohydrolase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.1.1.81	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964	C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0112	C		Seeded From UniProt	complete
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References

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