GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

MOUSE:PLXB2

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Plxnb2
Protein Name(s) Plexin-B2
External Links
UniProt B2RXS4
EMBL AK147538
AC113069
AC160538
CH466550
BC157960
BC157961
BC158086
BC172162
CCDS CCDS49698.1
RefSeq NP_001152993.1
NP_001271435.1
NP_620088.2
XP_006520475.1
XP_006520476.1
XP_011243751.1
XP_011243752.1
XP_011243753.1
UniGene Mm.267514
PDB 5E6P
PDBsum 5E6P
ProteinModelPortal B2RXS4
SMR B2RXS4
BioGrid 228283
IntAct B2RXS4
MINT B2RXS4
STRING 10090.ENSMUSP00000051731
iPTMnet B2RXS4
PhosphoSitePlus B2RXS4
SwissPalm B2RXS4
MaxQB B2RXS4
PaxDb B2RXS4
PeptideAtlas B2RXS4
PRIDE B2RXS4
Ensembl ENSMUST00000060808
ENSMUST00000109331
GeneID 140570
KEGG mmu:140570
UCSC uc007xfr.2
CTD 23654
MGI MGI:2154239
eggNOG ENOG410KCS6
ENOG411131Q
GeneTree ENSGT00760000119048
HOGENOM HOG000231376
HOVERGEN HBG053404
InParanoid B2RXS4
KO K06821
OMA KPFHGDI
OrthoDB EOG091G00EK
PhylomeDB B2RXS4
TreeFam TF312962
ChiTaRS Plxnb2
PRO PR:B2RXS4
Proteomes UP000000589
Bgee ENSMUSG00000036606
Genevisible B2RXS4
GO GO:0005887
GO:0017154
GO:0007420
GO:0007156
GO:0007162
GO:0001843
GO:0007405
GO:0050772
GO:0010976
GO:0008360
GO:0043087
GO:2001222
GO:0001932
GO:0071526
Gene3D 2.130.10.10
2.60.40.10
InterPro IPR013783
IPR014756
IPR002909
IPR031148
IPR013548
IPR002165
IPR016201
IPR008936
IPR001627
IPR036352
IPR015943
PANTHER PTHR22625
Pfam PF08337
PF01437
PF01403
PF01833
SMART SM00429
SM00423
SM00630
SUPFAM SSF101912
SSF48350
SSF81296
PROSITE PS51004

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0062023

collagen-containing extracellular matrix

PMID:28071719[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(UBERON:0000006)

Seeded From UniProt

complete

part_of

GO:0062023

collagen-containing extracellular matrix

PMID:22159717[2]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(UBERON:0002048)|part_of:(UBERON:0001155)

Seeded From UniProt

complete

involved_in

GO:1904861

excitatory synapse assembly

PMID:29981480[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:2001222

regulation of neuron migration

PMID:17554007[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071526

semaphorin-plexin signaling pathway

PMID:17554007[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0043087

regulation of GTPase activity

PMID:17554007[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0017154

semaphorin receptor activity

PMID:17554007[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0008360

regulation of cell shape

PMID:17554007[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007420

brain development

PMID:17554007[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007405

neuroblast proliferation

PMID:17554007[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21966369[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0001932

regulation of protein phosphorylation

PMID:17554007[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0001843

neural tube closure

PMID:17554007[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:1902287

semaphorin-plexin signaling pathway involved in axon guidance

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107683
MGI:MGI:2179061
PANTHER:PTN001098994

P

Seeded From UniProt

complete

involved_in

GO:0050772

positive regulation of axonogenesis

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2154238
MGI:MGI:2154239
PANTHER:PTN001861955

P

Seeded From UniProt

complete

involved_in

GO:0043087

regulation of GTPase activity

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2154239
PANTHER:PTN001861955
ZFIN:ZDB-GENE-030131-1620

P

Seeded From UniProt

complete

involved_in

GO:0030334

regulation of cell migration

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107684
MGI:MGI:2154244
PANTHER:PTN001098994

P

Seeded From UniProt

complete

enables

GO:0017154

semaphorin receptor activity

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107683
MGI:MGI:107684
MGI:MGI:107685
MGI:MGI:2154238
MGI:MGI:2154239
MGI:MGI:2154244
MGI:MGI:2179061
PANTHER:PTN001098994
UniProtKB:O43157
UniProtKB:Q9ULL4
WB:WBGene00004047
WB:WBGene00004048

F

Seeded From UniProt

complete

involved_in

GO:0008360

regulation of cell shape

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2154238
MGI:MGI:2154239
PANTHER:PTN001861955
UniProtKB:O43157

P

Seeded From UniProt

complete

involved_in

GO:0007162

negative regulation of cell adhesion

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001861955
UniProtKB:O43157
UniProtKB:Q9ULL4

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107684
MGI:MGI:2154239
MGI:MGI:2154244
PANTHER:PTN001098994
UniProtKB:O43157

C

Seeded From UniProt

complete

part_of

GO:0002116

semaphorin receptor complex

PMID:21873635[6]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001098994
UniProtKB:O43157

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0050772

positive regulation of axonogenesis

PMID:15330859[7]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:109244

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0010976

positive regulation of neuron projection development

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O15031

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007156

homophilic cell adhesion via plasma membrane adhesion molecules

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O15031

P

Seeded From UniProt

complete

involved_in

GO:0010976

positive regulation of neuron projection development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:O15031
ensembl:ENSP00000352288

P

Seeded From UniProt

complete

involved_in

GO:0007156

homophilic cell adhesion via plasma membrane adhesion molecules

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:O15031
ensembl:ENSP00000352288

P

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008936

P

Seeded From UniProt

complete

enables

GO:0017154

semaphorin receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR031148

F

Seeded From UniProt

complete

involved_in

GO:0071526

semaphorin-plexin signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR031148

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Naba, A et al. (2017) Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. Sci Rep 7 40495 PubMed GONUTS page
  2. ↑ Naba, A et al. (2012) The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. Mol. Cell Proteomics 11 M111.014647 PubMed GONUTS page
  3. ↑ McDermott, JE et al. (2018) Class 4 Semaphorins and Plexin-B receptors regulate GABAergic and glutamatergic synapse development in the mammalian hippocampus. Mol. Cell. Neurosci. 92 50-66 PubMed GONUTS page
  4. ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 Deng, S et al. (2007) Plexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivo. J. Neurosci. 27 6333-47 PubMed GONUTS page
  5. ↑ Roney, KE et al. (2011) Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activation. PLoS ONE 6 e24795 PubMed GONUTS page
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 6.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  7. ↑ Masuda, K et al. (2004) Sema4D stimulates axonal outgrowth of embryonic DRG sensory neurones. Genes Cells 9 821-9 PubMed GONUTS page
Retrieved from "https://gowiki.tamu.edu/wiki/index.php?title=MOUSE:PLXB2&oldid=5956078"