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MOUSE:PCSK1
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Pcsk1n | |
| Protein Name(s) | ProSAAS
IA-4 Proprotein convertase subtilisin/kexin type 1 inhibitor Proprotein convertase 1 inhibitor pro-SAAS KEP Big SAAS b-SAAS Little SAAS l-SAAS Big PEN-LEN b-PEN-LEN SAAS CT(1-49) PEN PEN-20 PEN-19 Little LEN l-LEN Big LEN b-LEN SAAS CT(25-40) | |
| External Links | ||
| UniProt | Q9QXV0 | |
| EMBL | AF181560 BC012263 | |
| CCDS | CCDS29979.1 | |
| RefSeq | NP_038920.2 | |
| UniGene | Mm.4881 | |
| ProteinModelPortal | Q9QXV0 | |
| BioGrid | 205954 | |
| IntAct | Q9QXV0 | |
| MINT | MINT-4130541 | |
| STRING | 10090.ENSMUSP00000040342 | |
| MEROPS | I49.001 | |
| PhosphoSite | Q9QXV0 | |
| MaxQB | Q9QXV0 | |
| PaxDb | Q9QXV0 | |
| PRIDE | Q9QXV0 | |
| Ensembl | ENSMUST00000041096 | |
| GeneID | 30052 | |
| KEGG | mmu:30052 | |
| UCSC | uc009snf.2 | |
| CTD | 27344 | |
| MGI | MGI:1353431 | |
| eggNOG | NOG46310 | |
| GeneTree | ENSGT00390000013488 | |
| HOGENOM | HOG000261638 | |
| HOVERGEN | HBG080210 | |
| InParanoid | Q9QXV0 | |
| OMA | RPVKEPR | |
| OrthoDB | EOG7KQ239 | |
| PhylomeDB | Q9QXV0 | |
| TreeFam | TF338201 | |
| NextBio | 307162 | |
| PRO | PR:Q9QXV0 | |
| Proteomes | UP000000589 | |
| Bgee | Q9QXV0 | |
| Genevestigator | Q9QXV0 | |
| GO | GO:0005615 GO:0070062 GO:0030141 GO:0005802 GO:0004867 GO:0010951 GO:0007218 GO:0016486 GO:0009409 GO:0002021 | |
| InterPro | IPR010832 | |
| PANTHER | PTHR15531 | |
| Pfam | PF07259 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1353431 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004866 |
endopeptidase inhibitor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000399123 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0030141 |
secretory granule |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0016486 |
peptide hormone processing |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0009409 |
response to cold |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
has_participant:(EMAPA:32845) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005802 |
trans-Golgi network |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3617 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004867 |
serine-type endopeptidase inhibitor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004866 |
endopeptidase inhibitor activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:3617 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0002021 |
response to dietary excess |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
has_participant:(EMAPA:32845) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004866 |
endopeptidase inhibitor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010951 |
negative regulation of endopeptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007218 |
neuropeptide signaling pathway |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Fricker, LD et al. (2000) Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing. J. Neurosci. 20 639-48 PubMed GONUTS page
- ↑ 3.0 3.1 Chakraborty, TR et al. (2006) Quantification of VGF- and pro-SAAS-derived peptides in endocrine tissues and the brain, and their regulation by diet and cold stress. Brain Res. 1089 21-32 PubMed GONUTS page
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