MOUSE:OX2G

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Cd200 (synonyms: Mox2)
Protein Name(s)	OX-2 membrane glycoprotein MRC OX-2 antigen
External Links
UniProt	O54901
EMBL	AF004023 AF029215 AF029214 AF231126
CCDS	CCDS49860.1
UniGene	Mm.245851
PDB	4BFI
PDBsum	4BFI
ProteinModelPortal	O54901
SMR	O54901
DIP	DIP-60157N
IntAct	O54901
MINT	MINT-4105943
PhosphoSite	O54901
MaxQB	O54901
PaxDb	O54901
PRIDE	O54901
MGI	MGI:1196990
eggNOG	NOG72791
HOGENOM	HOG000035940
HOVERGEN	HBG031790
InParanoid	O54901
ChiTaRS	Cd200
PRO	PR:O54901
Proteomes	UP000000589
CleanEx	MM_CD200
Genevestigator	O54901
GO	GO:0016021 GO:0005886
Gene3D	2.60.40.10
InterPro	IPR007110 IPR013783 IPR003596 IPR013151
Pfam	PF00047
SMART	SM00406
PROSITE	PS50835

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0043031	negative regulation of macrophage activation	PMID:11099416	ECO:0000315			P		Figure 2. Macrophage populations were activated in CD200-/- mice. This was observed in the increase of CD11b+ population and lymph node macrophages, and the change to a thick, multi-cell layer of MOMA-1+.	complete CACAO 6990
involved_in	GO:0150079	negative regulation of neuroinflammatory response	PMID:11099416	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(UBERON:0001016)	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:11099416	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000117)|part_of:(CL:0000236)|part_of:(CL:0000442)|part_of:(UBERON:0001986) part_of:(UBERON:0002106)	Seeded From UniProt	complete
involved_in	GO:0008285	negative regulation of cell population proliferation	PMID:11099416	ECO:0000315	mutant phenotype evidence used in manual assertion		P	acts_on_population_of:(CL:0002465)	Seeded From UniProt	complete
involved_in	GO:0043031	negative regulation of macrophage activation	PMID:11099416	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2000405	negative regulation of T cell migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3104	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1905522	negative regulation of macrophage migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3104	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1904465	negative regulation of matrix metallopeptidase secretion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41217	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1901215	negative regulation of neuron death	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3104	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1900165	negative regulation of interleukin-6 secretion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3104	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0150079	negative regulation of neuroinflammatory response	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3104	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0150077	regulation of neuroinflammatory response	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3104	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0150074	positive regulation of protein-glutamine gamma-glutamyltransferase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41217	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0150072	positive regulation of arginase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41217	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0098609	cell-cell adhesion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3104	P		Seeded From UniProt	complete
enables	GO:0086080	protein binding involved in heterotypic cell-cell adhesion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3104	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071636	positive regulation of transforming growth factor beta production	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41217	P		Seeded From UniProt	complete
part_of	GO:0044297	cell body	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41217	C		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41217	C		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3104	C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3104	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034113	heterotypic cell-cell adhesion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41217	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034113	heterotypic cell-cell adhesion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3104	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032793	positive regulation of CREB transcription factor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41217	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032088	negative regulation of NF-kappaB transcription factor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41217	P		Seeded From UniProt	complete
part_of	GO:0030424	axon	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41217	C		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41217	C		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3104	C		Seeded From UniProt	complete
involved_in	GO:0043031	negative regulation of macrophage activation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033321	P		Seeded From UniProt	complete
involved_in	GO:0050776	regulation of immune response	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033321	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
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References

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