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MOUSE:NIT2

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Nit2 (synonyms: D16Ertd502e)
Protein Name(s) Omega-amidase NIT2

Nitrilase homolog 2

External Links
UniProt Q9JHW2
EMBL AF284573
AK003604
AK004535
BC020153
CCDS CCDS37363.1
RefSeq NP_075664.1
UniGene Mm.383203
PDB 2W1V
PDBsum 2W1V
ProteinModelPortal Q9JHW2
SMR Q9JHW2
IntAct Q9JHW2
MINT MINT-4129730
PhosphoSite Q9JHW2
REPRODUCTION-2DPAGE IPI00119945
MaxQB Q9JHW2
PaxDb Q9JHW2
PRIDE Q9JHW2
Ensembl ENSMUST00000023432
GeneID 52633
KEGG mmu:52633
UCSC uc007zna.1
CTD 56954
MGI MGI:1261838
eggNOG COG0388
GeneTree ENSGT00550000074838
HOGENOM HOG000222700
HOVERGEN HBG105126
InParanoid Q9JHW2
KO K13566
OMA VGICYDM
OrthoDB EOG7XDBGD
PhylomeDB Q9JHW2
TreeFam TF300747
EvolutionaryTrace Q9JHW2
NextBio 309239
PRO PR:Q9JHW2
Proteomes UP000000589
Bgee Q9JHW2
CleanEx MM_NIT2
Genevestigator Q9JHW2
GO GO:0005813
GO:0070062
GO:0005739
GO:0050152
GO:0006528
GO:0006541
GO:0006107
Gene3D 3.60.110.10
InterPro IPR003010
Pfam PF00795
SUPFAM SSF56317
PROSITE PS50263

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0050152

omega-amidase activity

PMID:19464248[1]

ECO:0000314

F

The paper suggests necessary information and evidence about omega-amidase activity

complete
CACAO 10596

enables

GO:0050152

omega-amidase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000557480
TAIR:locus:2143039
UniProtKB:Q9NQR4

F

Seeded From UniProt

complete

involved_in

GO:0006541

glutamine metabolic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000557480
UniProtKB:Q9NQR4

P

Seeded From UniProt

complete

involved_in

GO:0006528

asparagine metabolic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000557480
UniProtKB:Q9NQR4

P

Seeded From UniProt

complete

involved_in

GO:0006107

oxaloacetate metabolic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000557480
TAIR:locus:2143039
UniProtKB:Q9NQR4

P

Seeded From UniProt

complete

enables

GO:0050152

omega-amidase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9NQR4

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006541

glutamine metabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9NQR4

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006528

asparagine metabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9NQR4

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006107

oxaloacetate metabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9NQR4

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9NQR4

C

Seeded From UniProt

complete

part_of

GO:0005813

centrosome

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9NQR4

C

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:14651853[3]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(EMAPA:16846)|part_of:(EMAPA:16894)|part_of:(EMAPA:17373)|part_of:(EMAPA:16105)

Seeded From UniProt

complete

enables

GO:0050152

omega-amidase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NQR4
ensembl:ENSP00000377696

F

Seeded From UniProt

complete

involved_in

GO:0006541

glutamine metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NQR4
ensembl:ENSP00000377696

P

Seeded From UniProt

complete

involved_in

GO:0006528

asparagine metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NQR4
ensembl:ENSP00000377696

P

Seeded From UniProt

complete

involved_in

GO:0006107

oxaloacetate metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NQR4
ensembl:ENSP00000377696

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NQR4
ensembl:ENSP00000377696

C

Seeded From UniProt

complete

part_of

GO:0005813

centrosome

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9NQR4
ensembl:ENSP00000377696

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:V9HW91
ensembl:ENSP00000377696

C

Seeded From UniProt

complete

part_of

GO:0005813

centrosome

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:V9HW91
ensembl:ENSP00000377696

C

Seeded From UniProt

complete

involved_in

GO:0006807

nitrogen compound metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003010

P

Seeded From UniProt

complete

enables

GO:0050152

omega-amidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.5.1.3

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Krasnikov, BF et al. (2009) Assay and purification of omega-amidase/Nit2, a ubiquitously expressed putative tumor suppressor, that catalyzes the deamidation of the alpha-keto acid analogues of glutamine and asparagine. Anal. Biochem. 391 144-50 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. Mootha, VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115 629-40 PubMed GONUTS page