MOUSE:NEK3

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Nek3
Protein Name(s)	Serine/threonine-protein kinase Nek3 Never in mitosis A-related kinase 3 NimA-related protein kinase 3
External Links
UniProt	Q9R0A5
EMBL	AF093416 AF099066 AC117665
CCDS	CCDS52519.1
RefSeq	NP_001156419.1 XP_006509174.1
UniGene	Mm.41413
ProteinModelPortal	Q9R0A5
SMR	Q9R0A5
PhosphoSite	Q9R0A5
MaxQB	Q9R0A5
PaxDb	Q9R0A5
PRIDE	Q9R0A5
Ensembl	ENSMUST00000110730 ENSMUST00000178324
GeneID	23954
KEGG	mmu:23954
UCSC	uc012gbb.1
CTD	4752
MGI	MGI:1344371
eggNOG	COG0515
GeneTree	ENSGT00760000118997
HOGENOM	HOG000261617
HOVERGEN	HBG003063
InParanoid	Q9R0A5
KO	K08857
OMA	RQWEKNV
NextBio	303780
PRO	PR:Q9R0A5
Proteomes	UP000000589
Bgee	Q9R0A5
ExpressionAtlas	Q9R0A5
Genevestigator	Q9R0A5
GO	GO:0030424 GO:0005737 GO:0005524 GO:0046872 GO:0004674 GO:0007067 GO:0006468
InterPro	IPR011009 IPR000719 IPR017441 IPR002290 IPR008271
Pfam	PF00069
SMART	SM00220
SUPFAM	SSF56112
PROSITE	PS00107 PS50011 PS00108

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0048812	neuron projection morphogenesis	PMID:19509051	ECO:0000315			P		Figure 3.	complete CACAO 6098
	GO:0030010	establishment of cell polarity	PMID:19509051	ECO:0000315			P		Figure 4 demonstrates NEK3 mutants producing many axons, indicative of a lack of neuron cell polarity.	complete CACAO 6099
	GO:0090043	regulation of tubulin deacetylation	PMID:19509051	ECO:0000315			P		Figure 5	complete CACAO 6100
involved_in	GO:0090043	regulation of tubulin deacetylation	PMID:19509051	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030010	establishment of cell polarity	PMID:19509051	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048812	neuron projection morphogenesis	PMID:19509051	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	PMID:19509051	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR008271	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR017441	F		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR008271	P		Seeded From UniProt	complete
part_of	GO:0042995	cell projection	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0966	C		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
involved_in	GO:0051301	cell division	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0132	P		Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
involved_in	GO:0007049	cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0131	P		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0723	F		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
part_of	GO:0030424	axon	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0279	C		Seeded From UniProt	complete
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References

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