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MOUSE:NCAN

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Ncan (synonyms: Cspg3)
Protein Name(s) Neurocan core protein

Chondroitin sulfate proteoglycan 3

External Links
UniProt P55066
EMBL X84727
BC065118
AK082298
CCDS CCDS22358.1
PIR S52781
RefSeq NP_031815.2
UniGene Mm.268079
ProteinModelPortal P55066
SMR P55066
IntAct P55066
MINT MINT-4092285
PhosphoSite P55066
MaxQB P55066
PaxDb P55066
PRIDE P55066
Ensembl ENSMUST00000002412
GeneID 13004
KEGG mmu:13004
UCSC uc009lys.2
CTD 1463
MGI MGI:104694
eggNOG NOG147231
GeneTree ENSGT00760000119025
HOGENOM HOG000170487
HOVERGEN HBG078994
InParanoid P55066
KO K06794
OrthoDB EOG7FFMQR
PhylomeDB P55066
TreeFam TF332134
Reactome REACT_196489
REACT_196514
REACT_196540
REACT_196606
REACT_198981
REACT_219680
REACT_236183
REACT_268952
REACT_268957
REACT_269050
REACT_269282
REACT_271176
NextBio 282828
PRO PR:P55066
Proteomes UP000000589
Bgee P55066
CleanEx MM_NCAN
Genevestigator P55066
GO GO:0005576
GO:0005886
GO:0005509
GO:0030246
GO:0005540
GO:0007155
GO:0051823
Gene3D 2.60.40.10
3.10.100.10
InterPro IPR001304
IPR016186
IPR018378
IPR016187
IPR000742
IPR001881
IPR013032
IPR000152
IPR018097
IPR007110
IPR013783
IPR003599
IPR013106
IPR000538
IPR000436
Pfam PF00059
PF00084
PF07686
PF00193
PRINTS PR01265
SMART SM00032
SM00034
SM00181
SM00179
SM00409
SM00445
SUPFAM SSF56436
SSF57535
PROSITE PS00010
PS00615
PS50041
PS00022
PS01186
PS50026
PS01187
PS50835
PS01241
PS50963
PS50923

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0031012

extracellular matrix

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:102889
MGI:MGI:1096385
MGI:MGI:1337006
MGI:MGI:2137300
MGI:MGI:99602
PANTHER:PTN001105676

C

Seeded From UniProt

complete

involved_in

GO:0007417

central nervous system development

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001105676
RGD:68358

P

Seeded From UniProt

complete

involved_in

GO:0001501

skeletal system development

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001105676
ZFIN:ZDB-GENE-030131-2185

P

Seeded From UniProt

complete

part_of

GO:0072534

perineuronal net

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:619941

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0051823

regulation of synapse structural plasticity

PMID:11486035[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2182149

P

regulates_o_occurs_in:(EMAPA:32845)

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:619941

C

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001881
InterPro:IPR018097

F

Seeded From UniProt

complete

enables

GO:0005540

hyaluronic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000538

F

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000538

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

Reactome:R-MMU-443770

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0130

P

Seeded From UniProt

complete

enables

GO:0005540

hyaluronic acid binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0373

F

Seeded From UniProt

complete

enables

GO:0030246

carbohydrate binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0430

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Zhou, XH et al. (2001) Neurocan is dispensable for brain development. Mol. Cell. Biol. 21 5970-8 PubMed GONUTS page