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MOUSE:MYH11
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Myh11 | |
| Protein Name(s) | Myosin-11
Myosin heavy chain 11 Myosin heavy chain, smooth muscle isoform SMMHC | |
| External Links | ||
| UniProt | O08638 | |
| EMBL | D85923 D85924 L25860 S81516 | |
| CCDS | CCDS27972.1 | |
| PIR | I52863 JC5420 JC5421 | |
| UniGene | Mm.250705 | |
| ProteinModelPortal | O08638 | |
| SMR | O08638 | |
| IntAct | O08638 | |
| MINT | MINT-4102706 | |
| PhosphoSite | O08638 | |
| MaxQB | O08638 | |
| PaxDb | O08638 | |
| PRIDE | O08638 | |
| MGI | MGI:102643 | |
| eggNOG | COG5022 | |
| HOGENOM | HOG000173958 | |
| HOVERGEN | HBG004704 | |
| InParanoid | O08638 | |
| PhylomeDB | O08638 | |
| ChiTaRS | Myh11 | |
| PRO | PR:O08638 | |
| Proteomes | UP000000589 | |
| CleanEx | MM_MYH11 | |
| Genevestigator | O08638 | |
| GO | GO:0042470 GO:0005859 GO:0030016 GO:0016459 GO:0032982 GO:0030485 GO:0001725 GO:0005524 GO:0003774 GO:0008307 GO:0048739 GO:0048251 GO:0008152 GO:0030241 GO:0006939 | |
| Gene3D | 4.10.270.10 | |
| InterPro | IPR000048 IPR027401 IPR001609 IPR004009 IPR002928 IPR027417 | |
| Pfam | PF00063 PF02736 PF01576 | |
| PRINTS | PR00193 | |
| SMART | SM00015 SM00242 | |
| SUPFAM | SSF52540 | |
| PROSITE | PS50096 PS51456 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005903 |
brush border |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0000584) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0048739 |
cardiac muscle fiber development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0048251 |
elastic fiber assembly |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030241 |
skeletal muscle myosin thick filament assembly |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008307 |
structural constituent of muscle |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006939 |
smooth muscle contraction |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0048739 |
cardiac muscle fiber development |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0048251 |
elastic fiber assembly |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030485 |
smooth muscle contractile fiber |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016459 |
myosin complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008307 |
structural constituent of muscle |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0006939 |
smooth muscle contraction |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3576856 |
P |
occurs_in:(EMAPA:28637) |
Seeded From UniProt |
complete | |
|
acts_upstream_of_or_within |
GO:0006939 |
smooth muscle contraction |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2656492 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0006939 |
smooth muscle contraction |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005859 |
muscle myosin complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005859 |
muscle myosin complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003774 |
motor activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2656492 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0001725 |
stress fiber |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003774 |
motor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001609 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016459 |
myosin complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051015 |
actin filament binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032982 |
myosin filament |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016459 |
myosin complex |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005516 |
calmodulin binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003779 |
actin binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030016 |
myofibril |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042470 |
melanosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Revenu, C et al. (2012) A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins. Mol. Biol. Cell 23 324-36 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Babu, GJ et al. (2001) Loss of SM-B myosin affects muscle shortening velocity and maximal force development. Nat. Cell Biol. 3 1025-9 PubMed GONUTS page
- ↑ 3.0 3.1 Suzuki, T et al. (1996) Preferential differentiation of P19 mouse embryonal carcinoma cells into smooth muscle cells. Use of retinoic acid and antisense against the central nervous system-specific POU transcription factor Brn-2. Circ. Res. 78 395-404 PubMed GONUTS page
- ↑ Karagiannis, P et al. (2003) The smooth muscle myosin seven amino acid heavy chain insert's kinetic role in the crossbridge cycle for mouse bladder. J. Physiol. (Lond.) 547 463-73 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Morano, I et al. (2000) Smooth-muscle contraction without smooth-muscle myosin. Nat. Cell Biol. 2 371-5 PubMed GONUTS page
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