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MOUSE:MO2R1
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Cd200r1 (synonyms: Mox2r, Ox2r) | |
| Protein Name(s) | Cell surface glycoprotein CD200 receptor 1
CD200 cell surface glycoprotein receptor Cell surface glycoprotein OX2 receptor 1 | |
| External Links | ||
| UniProt | Q9ES57 | |
| EMBL | AF231393 BC052682 | |
| CCDS | CCDS28189.1 | |
| RefSeq | NP_067300.1 | |
| UniGene | Mm.416152 | |
| PDB | 4BFG 4BFI | |
| PDBsum | 4BFG 4BFI | |
| ProteinModelPortal | Q9ES57 | |
| SMR | Q9ES57 | |
| BioGrid | 208327 | |
| DIP | DIP-60159N | |
| STRING | 10090.ENSMUSP00000053822 | |
| PhosphoSite | Q9ES57 | |
| PRIDE | Q9ES57 | |
| Ensembl | ENSMUST00000057488 | |
| GeneID | 57781 | |
| KEGG | mmu:57781 | |
| UCSC | uc007zhr.2 | |
| CTD | 131450 | |
| MGI | MGI:1889024 | |
| eggNOG | NOG25299 | |
| GeneTree | ENSGT00390000014496 | |
| HOGENOM | HOG000113622 | |
| HOVERGEN | HBG108141 | |
| InParanoid | Q9ES57 | |
| OMA | LCPWRTA | |
| OrthoDB | EOG7RZ5QQ | |
| PhylomeDB | Q9ES57 | |
| TreeFam | TF335960 | |
| Reactome | REACT_202937 | |
| NextBio | 313964 | |
| PRO | PR:Q9ES57 | |
| Proteomes | UP000000589 | |
| Bgee | Q9ES57 | |
| CleanEx | MM_CD200R1 | |
| ExpressionAtlas | Q9ES57 | |
| Genevestigator | Q9ES57 | |
| GO | GO:0009897 GO:0016021 GO:0043235 GO:0004872 | |
| Gene3D | 2.60.40.10 | |
| InterPro | IPR013162 IPR007110 IPR013783 IPR003599 IPR013106 | |
| Pfam | PF08205 PF07686 | |
| SMART | SM00409 | |
| PROSITE | PS50835 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0042098 |
T cell proliferation |
ECO:0000315 |
P |
In figure 3 one can see that in mice that have CD200R1−/− mice T-cell proliferation has increased |
complete | |||||
|
enables |
GO:0038023 |
signaling receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1889024 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0009897 |
external side of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1889024 |
C |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:2000405 |
negative regulation of T cell migration |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61837 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:1905522 |
negative regulation of macrophage migration |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61837 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:1901215 |
negative regulation of neuron death |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61837 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:1900165 |
negative regulation of interleukin-6 secretion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61837 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0150079 |
negative regulation of neuroinflammatory response |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61837 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0150077 |
regulation of neuroinflammatory response |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61837 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0086080 |
protein binding involved in heterotypic cell-cell adhesion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61837 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043235 |
receptor complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0038023 |
signaling receptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0034113 |
heterotypic cell-cell adhesion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61837 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0009986 |
cell surface |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009986 |
cell surface |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61837 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0009897 |
external side of plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0038023 |
signaling receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0150077 |
regulation of neuroinflammatory response |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Hauser, K et al. (1985) Trimipramine, a tricyclic antidepressant exerting atypical actions on the central noradrenergic system. Eur. J. Pharmacol. 111 23-30 PubMed GONUTS page
- ↑ 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Ghai, R et al. (2013) Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proc. Natl. Acad. Sci. U.S.A. 110 E643-52 PubMed GONUTS page
- ↑ 4.0 4.1 Gorczynski, RM et al. (2004) Structural and functional heterogeneity in the CD200R family of immunoregulatory molecules and their expression at the feto-maternal interface. Am. J. Reprod. Immunol. 52 147-63 PubMed GONUTS page
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