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MOUSE:LSR
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Lsr (synonyms: Lisch7) | |
| Protein Name(s) | Lipolysis-stimulated lipoprotein receptor
Lipolysis-stimulated receptor Liver-specific bHLH-Zip transcription factor Liver-specific gene on mouse chromosome 7 protein | |
| External Links | ||
| UniProt | Q99KG5 | |
| EMBL | U49507 U49508 AK146807 AK167463 BC004672 AY376636 | |
| CCDS | CCDS21119.1 CCDS52185.1 CCDS52186.1 | |
| RefSeq | NP_001157656.1 NP_001157657.1 NP_059101.1 | |
| UniGene | Mm.4067 | |
| ProteinModelPortal | Q99KG5 | |
| SMR | Q99KG5 | |
| BioGrid | 207572 | |
| IntAct | Q99KG5 | |
| PhosphoSite | Q99KG5 | |
| MaxQB | Q99KG5 | |
| PaxDb | Q99KG5 | |
| PRIDE | Q99KG5 | |
| Ensembl | ENSMUST00000001279 ENSMUST00000098553 ENSMUST00000108116 | |
| GeneID | 54135 | |
| KEGG | mmu:54135 | |
| UCSC | uc009ghj.2 uc009ghk.2 uc009ghl.2 | |
| CTD | 51599 | |
| MGI | MGI:1927471 | |
| eggNOG | NOG72582 | |
| GeneTree | ENSGT00430000030906 | |
| HOGENOM | HOG000253962 | |
| HOVERGEN | HBG061576 | |
| InParanoid | Q99KG5 | |
| OMA | HSRDPHY | |
| OrthoDB | EOG7B8S3X | |
| PhylomeDB | Q99KG5 | |
| TreeFam | TF330877 | |
| NextBio | 310945 | |
| PRO | PR:Q99KG5 | |
| Proteomes | UP000000589 | |
| Bgee | Q99KG5 | |
| CleanEx | MM_LSR | |
| ExpressionAtlas | Q99KG5 | |
| Genevestigator | Q99KG5 | |
| GO | GO:0042627 GO:0070062 GO:0016021 GO:0034362 GO:0005886 GO:0034361 GO:0030228 GO:0030169 GO:0042953 GO:0001889 GO:0006898 GO:0019216 | |
| Gene3D | 2.60.40.10 | |
| InterPro | IPR013783 IPR003599 IPR008664 | |
| Pfam | PF05624 | |
| SMART | SM00409 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0060856 |
establishment of blood-brain barrier |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1904274 |
tricellular tight junction assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0061689 |
tricellular tight junction |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0061689 |
tricellular tight junction |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001889 |
liver development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0019216 |
regulation of lipid metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:69236 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016192 |
vesicle-mediated transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0030228 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019216 |
regulation of lipid metabolic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9WU74 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0061689 |
tricellular tight junction |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042953 |
lipoprotein transport |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030228 |
lipoprotein particle receptor activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030169 |
low-density lipoprotein particle binding |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
Reactome:R-MMU-8933295 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
part_of |
GO:0034361 |
very-low-density lipoprotein particle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042627 |
chylomicron |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0034362 |
low-density lipoprotein particle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Sohet, F et al. (2015) LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation. J. Cell Biol. 208 703-11 PubMed GONUTS page
- ↑ 2.0 2.1 Furuse, M et al. (2012) Lipolysis-stimulated lipoprotein receptor: a novel membrane protein of tricellular tight junctions. Ann. N. Y. Acad. Sci. 1257 54-8 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Mesli, S et al. (2004) Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR-/- embryos at 12.5 to 14.5 days of gestation. Eur. J. Biochem. 271 3103-14 PubMed GONUTS page
- ↑ Nakatsu, D et al. (2014) JNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheet. Genes Cells 19 565-81 PubMed GONUTS page
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