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MOUSE:LPCT4

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Lpcat4 (synonyms: Agpat7, Aytl3)
Protein Name(s) Lysophospholipid acyltransferase LPCAT4

1-acylglycerol-3-phosphate O-acyltransferase 7 1-AGP acyltransferase 7 1-AGPAT 7 1-acylglycerophosphocholine O-acyltransferase 1-acylglycerophosphoserine O-acyltransferase 1-alkenylglycerophosphoethanolamine O-acyltransferase 1-alkylglycerophosphocholine O-acetyltransferase Acyltransferase-like 3 Lysophosphatidylcholine acyltransferase 4 Lysophosphatidylethanolamine acyltransferase 2 Plasmalogen synthase

External Links
UniProt Q6NVG1
EMBL BC068131
BC080829
CCDS CCDS16548.1
RefSeq NP_997089.1
UniGene Mm.33438
ProteinModelPortal Q6NVG1
SMR Q6NVG1
PhosphoSite Q6NVG1
MaxQB Q6NVG1
PaxDb Q6NVG1
PRIDE Q6NVG1
Ensembl ENSMUST00000028554
GeneID 99010
KEGG mmu:99010
UCSC uc008loo.1
CTD 254531
MGI MGI:2138993
eggNOG NOG236173
GeneTree ENSGT00390000004914
HOGENOM HOG000234374
InParanoid Q6NVG1
KO K13512
OMA LRPPHTS
OrthoDB EOG7NCV5G
PhylomeDB Q6NVG1
TreeFam TF323244
Reactome REACT_188640
REACT_199027
REACT_199030
REACT_199038
REACT_199039
REACT_237947
UniPathway UPA00085
NextBio 353751
PRO PR:Q6NVG1
Proteomes UP000000589
Bgee Q6NVG1
Genevestigator Q6NVG1
GO GO:0005783
GO:0005789
GO:0016021
GO:0047184
GO:0047166
GO:0047192
GO:0071617
GO:0008654
GO:0006644
InterPro IPR002123
Pfam PF01553
SMART SM00563

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0003841

1-acylglycerol-3-phosphate O-acyltransferase activity

PMID:19114731[1]

ECO:0000314

F

Figures 4 shows the Acyltransferase activity measured by the transfer of [1-14C]acyl-CoAs or [3H]acetyl-CoA to lysophospholipids to form phospholipids. The lysophospholipid preferences of mLPAAT3 were determined. The substrate specificity of the mLPAAT3 enzyme was measure using [1-14C]arachidonoyl-CoA as an acyl donor, and using a variety of lysophospholipid acceptors.

complete
CACAO 4374

enables

GO:0071617

lysophospholipid acyltransferase activity

PMID:18458083[2]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q643R3

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006644

phospholipid metabolic process

PMID:18458083[2]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q643R3

P

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

PMID:18458083[2]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q643R3

C

Seeded From UniProt

complete

enables

GO:0071617

lysophospholipid acyltransferase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q643R3
ensembl:ENSP00000317300

F

Seeded From UniProt

complete

involved_in

GO:0006644

phospholipid metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q643R3
ensembl:ENSP00000317300

P

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q643R3
ensembl:ENSP00000317300

C

Seeded From UniProt

complete

enables

GO:0016746

transferase activity, transferring acyl groups

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002123

F

Seeded From UniProt

complete

enables

GO:0047166

1-alkenylglycerophosphoethanolamine O-acyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.3.1.121

F

Seeded From UniProt

complete

enables

GO:0047184

1-acylglycerophosphocholine O-acyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.3.1.23

F

Seeded From UniProt

complete

enables

GO:0047192

1-alkylglycerophosphocholine O-acetyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.3.1.67

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256

C

Seeded From UniProt

complete

enables

GO:0016746

transferase activity, transferring acyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0012

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0443

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0008654

phospholipid biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0594

P

Seeded From UniProt

complete

part_of

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0097

C

Seeded From UniProt

complete

involved_in

GO:0006644

phospholipid metabolic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00085

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Yuki, K et al. (2009) Characterization of mouse lysophosphatidic acid acyltransferase 3: an enzyme with dual functions in the testis. J. Lipid Res. 50 860-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 Cao, J et al. (2008) Molecular identification of a novel mammalian brain isoform of acyl-CoA:lysophospholipid acyltransferase with prominent ethanolamine lysophospholipid acylating activity, LPEAT2. J. Biol. Chem. 283 19049-57 PubMed GONUTS page