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MOUSE:LORI

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Lor
Protein Name(s) Loricrin
External Links
UniProt P18165
EMBL M34398
U09189
BC026781
BC058223
CCDS CCDS17546.1
PIR A35628
RefSeq NP_032534.2
UniGene Mm.1121
ProteinModelPortal P18165
STRING 10090.ENSMUSP00000052128
PhosphoSite P18165
PRIDE P18165
Ensembl ENSMUST00000058150
GeneID 16939
KEGG mmu:16939
UCSC uc008qdk.1
CTD 4014
MGI MGI:96816
eggNOG NOG145891
KO K10385
OMA FSAHAKQ
NextBio 290988
PRO PR:P18165
Proteomes UP000000589
Bgee P18165
CleanEx MM_LOR
Genevestigator P18165
GO GO:0001533
GO:0005737
GO:0009898
GO:0005200
GO:0030280
GO:0031424

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0030280

structural constituent of epidermis

PMID:2190691[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0030280

structural constituent of epidermis

PMID:11038185[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0009898

cytoplasmic side of plasma membrane

PMID:2190691[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:11698679[3]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P23490

C

Seeded From UniProt

complete

enables

GO:0005200

structural constituent of cytoskeleton

PMID:2190691[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0001533

cornified envelope

PMID:21930775[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0001533

cornified envelope

PMID:2190691[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0001533

cornified envelope

PMID:14673151[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0001533

cornified envelope

PMID:11698679[3]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P23490

C

Seeded From UniProt

complete

involved_in

GO:0007010

cytoskeleton organization

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005200

P

Seeded From UniProt

complete

part_of

GO:0001533

cornified envelope

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR031700

C

Seeded From UniProt

complete

enables

GO:0030280

structural constituent of epidermis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR031700

F

Seeded From UniProt

complete

involved_in

GO:0031424

keratinization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0417

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Mehrel, T et al. (1990) Identification of a major keratinocyte cell envelope protein, loricrin. Cell 61 1103-12 PubMed GONUTS page
  2. Koch, PJ et al. (2000) Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein. J. Cell Biol. 151 389-400 PubMed GONUTS page
  3. 3.0 3.1 Marshall, D et al. (2001) Differentially expressed late constituents of the epidermal cornified envelope. Proc. Natl. Acad. Sci. U.S.A. 98 13031-6 PubMed GONUTS page
  4. Fessing, MY et al. (2011) p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J. Cell Biol. 194 825-39 PubMed GONUTS page
  5. Cheng, X et al. (2004) Assessment of splice variant-specific functions of desmocollin 1 in the skin. Mol. Cell. Biol. 24 154-63 PubMed GONUTS page