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MOUSE:K2C6A
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Krt6a (synonyms: Ker2, Krt2-6, Krt2-6a, Krt6) | |
| Protein Name(s) | Keratin, type II cytoskeletal 6A
Cytokeratin-6A CK-6A Keratin-6-alpha mK6-alpha Keratin-6A K6A | |
| External Links | ||
| UniProt | P50446 | |
| EMBL | K02108 AB012033 BC080820 | |
| CCDS | CCDS27860.1 | |
| PIR | I59009 | |
| RefSeq | NP_032502.3 | |
| UniGene | Mm.302399 | |
| ProteinModelPortal | P50446 | |
| SMR | P50446 | |
| BioGrid | 201035 | |
| IntAct | P50446 | |
| MINT | MINT-1859525 | |
| STRING | 10090.ENSMUSP00000023788 | |
| PhosphoSite | P50446 | |
| MaxQB | P50446 | |
| PaxDb | P50446 | |
| PRIDE | P50446 | |
| Ensembl | ENSMUST00000023788 | |
| GeneID | 16687 | |
| KEGG | mmu:16687 | |
| UCSC | uc007xtv.1 | |
| CTD | 3853 | |
| MGI | MGI:1100845 | |
| eggNOG | NOG315845 | |
| GeneTree | ENSGT00760000118796 | |
| HOGENOM | HOG000230976 | |
| HOVERGEN | HBG013015 | |
| InParanoid | P50446 | |
| KO | K07605 | |
| OMA | MQDQVED | |
| OrthoDB | EOG7FV3Q8 | |
| PhylomeDB | P50446 | |
| TreeFam | TF317854 | |
| ChiTaRS | Krt6a | |
| NextBio | 290437 | |
| PRO | PR:P50446 | |
| Proteomes | UP000000589 | |
| Bgee | P50446 | |
| CleanEx | MM_KRT6A | |
| ExpressionAtlas | P50446 | |
| Genevestigator | P50446 | |
| GO | GO:0045095 GO:0005198 GO:0045109 GO:0031424 GO:0002009 GO:0016055 | |
| InterPro | IPR001664 IPR018039 IPR003054 | |
| PANTHER | PTHR23239 | |
| Pfam | PF00038 | |
| PRINTS | PR01276 | |
| PROSITE | PS00226 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0050830 |
defense response to Gram-positive bacterium |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0061844 |
antimicrobial humoral immune response mediated by antimicrobial peptide |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0044140 |
negative regulation of growth of symbiont on or near host surface |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0002009 |
morphogenesis of an epithelium |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042060 |
wound healing |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0045109 |
intermediate filament organization |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:1333768 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0031424 |
keratinization |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:1333768 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0016055 |
Wnt signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0002009 |
morphogenesis of an epithelium |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:1333768 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005198 |
structural molecule activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005882 |
intermediate filament |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045095 |
keratin filament |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005882 |
intermediate filament |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Tam, C et al. (2012) Cytokeratins mediate epithelial innate defense through their antimicrobial properties. J. Clin. Invest. 122 3665-77 PubMed GONUTS page
- ↑ 2.0 2.1 Wojcik, SM et al. (2000) Delayed wound healing in keratin 6a knockout mice. Mol. Cell. Biol. 20 5248-55 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Wong, P et al. (2005) Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice. Mol. Cell. Biol. 25 197-205 PubMed GONUTS page
- ↑ Miranda-Carboni, GA et al. (2008) A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors. Genes Dev. 22 3121-34 PubMed GONUTS page
