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MOUSE:HBB1
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Hbb-b1 | |
| Protein Name(s) | Hemoglobin subunit beta-1
Beta-1-globin Hemoglobin beta-1 chain Hemoglobin beta-major chain | |
| External Links | ||
| UniProt | P02088 | |
| EMBL | X14061 J00413 AB020013 AB020015 AK002258 AK002394 AK003096 AK003472 AK005442 AK005490 AK005496 AK010873 AK010902 AK010980 AK010981 AK010991 AK010993 AK011006 AK011013 AK011016 AK011027 AK011033 AK011050 AK011052 AK011053 AK011057 AK011067 AK011069 AK011075 AK011077 AK011083 AK011102 AK012551 AK014364 AK027903 AK027904 AK028067 AK088149 AK133714 AK147001 AK160629 AK161021 AK165490 AK167615 AK168412 AK168477 AK168562 AK168584 AK168819 AK168826 AK168846 M19236 M10828 M10830 M10829 M10688 | |
| PIR | A90790 | |
| RefSeq | NP_001188320.1 NP_001265090.1 NP_032246.2 | |
| UniGene | Mm.288567 Mm.467412 | |
| PDB | 1JEB 3HRW | |
| PDBsum | 1JEB 3HRW | |
| ProteinModelPortal | P02088 | |
| SMR | P02088 | |
| BioGrid | 200219 | |
| IntAct | P02088 | |
| MINT | MINT-4097231 | |
| PhosphoSite | P02088 | |
| REPRODUCTION-2DPAGE | IPI00553333 P02088 | |
| SWISS-2DPAGE | P02088 | |
| MaxQB | P02088 | |
| PaxDb | P02088 | |
| PRIDE | P02088 | |
| DNASU | 15129 | |
| GeneID | 100503605 101488143 15129 | |
| KEGG | mmu:100503605 mmu:101488143 mmu:15129 | |
| CTD | 100503605 101488143 15129 | |
| MGI | MGI:96021 | |
| eggNOG | NOG269316 | |
| HOVERGEN | HBG009709 | |
| InParanoid | P02088 | |
| KO | K13823 | |
| PhylomeDB | P02088 | |
| ChiTaRS | Hbb-b1 | |
| EvolutionaryTrace | P02088 | |
| NextBio | 287582 | |
| PRO | PR:P02088 | |
| Proteomes | UP000000589 | |
| CleanEx | MM_HBB-B1 | |
| Genevestigator | P02088 | |
| GO | GO:0005833 GO:0020037 GO:0005506 GO:0019825 GO:0005344 | |
| Gene3D | 1.10.490.10 | |
| InterPro | IPR000971 IPR009050 IPR012292 IPR002337 | |
| Pfam | PF00042 | |
| PRINTS | PR00814 | |
| SUPFAM | SSF46458 | |
| PROSITE | PS01033 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0043209 |
myelin sheath |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(CL:0000128) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0043177 |
organic acid binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000154218 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042744 |
hydrogen peroxide catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000154218 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0031838 |
haptoglobin-hemoglobin complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000154218 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0031721 |
hemoglobin alpha binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000154350 |
F |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0031720 |
haptoglobin binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000154218 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0020037 |
heme binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000154218 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0019825 |
oxygen binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96022 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0019825 |
oxygen binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96022 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005833 |
hemoglobin complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96021 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005344 |
oxygen carrier activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96021 |
F |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0004601 |
peroxidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000154218 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005833 |
hemoglobin complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005344 |
oxygen carrier activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2384424 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0048821 |
erythrocyte development |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:96022 |
P |
results_in_development_of:(CL:0000232) |
Seeded From UniProt |
complete | |
|
acts_upstream_of_or_within |
GO:0030097 |
hemopoiesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2384424 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0015671 |
oxygen transport |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2384424 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0010999 |
regulation of eIF2 alpha phosphorylation by heme |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857179 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005833 |
hemoglobin complex |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857295 |
C |
part_of:(CL:0000232) |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0098869 |
cellular oxidant detoxification |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004601 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005833 |
hemoglobin complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015671 |
oxygen transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019825 |
oxygen binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0020037 |
heme binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005344 |
oxygen carrier activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015671 |
oxygen transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Werner, HB et al. (2007) Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. J. Neurosci. 27 7717-30 PubMed GONUTS page
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Suzuki, Y et al. (2002) Model mice for Presbyterian hemoglobinopathy (Asn(beta108)-->Lys) confer hemolytic anemia with altered oxygen affinity and instability of Hb. Biochem. Biophys. Res. Commun. 295 869-76 PubMed GONUTS page
- ↑ 4.0 4.1 Yang, B et al. (1995) A mouse model for beta 0-thalassemia. Proc. Natl. Acad. Sci. U.S.A. 92 11608-12 PubMed GONUTS page
- ↑ Han, AP et al. (2005) Heme-regulated eIF2alpha kinase modifies the phenotypic severity of murine models of erythropoietic protoporphyria and beta-thalassemia. J. Clin. Invest. 115 1562-70 PubMed GONUTS page
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