MOUSE:GAN

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Gan (ECO:0000312 with MGI:MGI:1890619)
Protein Name(s)	Gigaxonin (ECO:0000312 with MGI:MGI:1890619)
External Links
UniProt	Q8CA72
EMBL	AC121116 AK039455 BC112432
CCDS	CCDS40490.1
RefSeq	NP_001074620.1
UniGene	Mm.132992
ProteinModelPortal	Q8CA72
SMR	Q8CA72
IntAct	Q8CA72
STRING	10090.ENSMUSP00000070168
PhosphoSite	Q8CA72
MaxQB	Q8CA72
PaxDb	Q8CA72
PRIDE	Q8CA72
DNASU	209239
Ensembl	ENSMUST00000064488
GeneID	209239
KEGG	mmu:209239
UCSC	uc009nox.1
CTD	8139
MGI	MGI:1890619
eggNOG	NOG274392
GeneTree	ENSGT00760000119153
HOGENOM	HOG000290709
HOVERGEN	HBG005802
InParanoid	Q8CA72
KO	K10453
OMA	IQGSEMV
PhylomeDB	Q8CA72
TreeFam	TF329218
Reactome	REACT_199115
UniPathway	UPA00143
NextBio	372602
PRO	PR:Q8CA72
Proteomes	UP000000589
Bgee	Q8CA72
Genevestigator	Q8CA72
GO	GO:0031463 GO:0005737 GO:0005856 GO:0007010 GO:0016567
Gene3D	2.120.10.80
InterPro	IPR011705 IPR000210 IPR011333 IPR013069 IPR017096 IPR015915 IPR006652
Pfam	PF07707 PF00651 PF01344
PIRSF	PIRSF037037
SMART	SM00875 SM00225 SM00612
SUPFAM	SSF54695
PROSITE	PS50097

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0005856	cytoskeleton	PMID:23585478	ECO:0000315			C		From figure 2A and 2B, it is shown that the mutant version of gigaxonin, named S52G gigaxonin, was unable to remove vimentin while WT gigaxonin was able to remove it. This proved that gigaxonin was able to affect VIFs but not other cytoskeletal proteins.	complete CACAO 8752
part_of	GO:0031463	Cul3-RING ubiquitin ligase complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9H2C0	C		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9H2C0	P		Seeded From UniProt	complete
part_of	GO:0031463	Cul3-RING ubiquitin ligase complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9H2C0	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0016567	protein ubiquitination	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9H2C0	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007010	cytoskeleton organization	PMID:11062483	ECO:0000266	sequence orthology evidence used in manual assertion	EMBL:AF291673	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9H2C0	C		Seeded From UniProt	complete
part_of	GO:0031463	Cul3-RING ubiquitin ligase complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9H2C0 ensembl:ENSP00000476795	C		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9H2C0 ensembl:ENSP00000476795	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9H2C0 ensembl:ENSP00000476795	C		Seeded From UniProt	complete
involved_in	GO:0007010	cytoskeleton organization	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030579	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
part_of	GO:0005856	cytoskeleton	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0206 UniProtKB-SubCell:SL-0090	C		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00143	P		Seeded From UniProt	complete
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References

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