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MOUSE:F8VPS6
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Protein Plekhg4 (ECO:0000313 with Ensembl:ENSMUSP00000014927) | |
| External Links | ||
| UniProt | F8VPS6 | |
| EMBL | AC124584 | |
| RefSeq | NP_001074802.1 | |
| UniGene | Mm.32034 | |
| ProteinModelPortal | F8VPS6 | |
| SMR | F8VPS6 | |
| PRIDE | F8VPS6 | |
| Ensembl | ENSMUST00000014927 | |
| GeneID | 102075 | |
| KEGG | mmu:102075 | |
| UCSC | uc009ncw.1 | |
| CTD | 25894 | |
| MGI | MGI:2142544 | |
| GeneTree | ENSGT00760000119030 | |
| InParanoid | F8VPS6 | |
| OMA | LQPLAGW | |
| TreeFam | TF334329 | |
| NextBio | 355260 | |
| PRO | PR:F8VPS6 | |
| Proteomes | UP000000589 | |
| Bgee | F8VPS6 | |
| ExpressionAtlas | F8VPS6 | |
| GO | GO:0005089 | |
| Gene3D | 1.20.900.10 2.30.29.30 | |
| InterPro | IPR000219 IPR001849 IPR011993 | |
| Pfam | PF00621 | |
| SMART | SM00233 SM00325 | |
| SUPFAM | SSF48065 | |
| PROSITE | PS50010 PS50003 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0032956 |
regulation of actin cytoskeleton organization |
ECO:0000315 |
P |
Insets of fluorescent microscopy in Fig. 4 show cytoskeletal features exhibited by Plekhg4 expression, demonstrating how it plays a role in the regulation the actin cytoskeleton |
complete | |||||
|
involved_in |
GO:0090630 |
activation of GTPase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:0090630 |
activation of GTPase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Plekhg4-GTPase association is demonstrated in Fig 3. B, and the GTPase activation by Plekhg4 is shown in Fig 3. A. Together these results demonstrate Plekhg4’s GEF function. |
complete | ||||
|
part_of |
GO:0005575 |
cellular_component |
ECO:0000307 |
no biological data found used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003674 |
molecular_function |
ECO:0000307 |
no biological data found used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005089 |
Rho guanyl-nucleotide exchange factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035023 |
regulation of Rho protein signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Gupta, M et al. (2013) Plekhg4 is a novel Dbl family guanine nucleotide exchange factor protein for rho family GTPases. J. Biol. Chem. 288 14522-30 PubMed GONUTS page