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MOUSE:ENTP1

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Entpd1 (synonyms: Cd39)
Protein Name(s) Ectonucleoside triphosphate diphosphohydrolase 1

NTPDase 1 Ecto-ATP diphosphohydrolase 1 Ecto-ATPDase 1 Ecto-ATPase 1 Ecto-apyrase Lymphoid cell activation antigen

External Links
UniProt P55772
EMBL AF037366
AF041818
AF041812
AF041813
AF041814
AF041815
AF041816
AF041817
CCDS CCDS50434.1
RefSeq NP_033978.1
UniGene Mm.2824
ProteinModelPortal P55772
SMR P55772
PhosphoSite P55772
MaxQB P55772
PaxDb P55772
PRIDE P55772
Ensembl ENSMUST00000112231
GeneID 12495
KEGG mmu:12495
UCSC uc008hlf.1
CTD 953
MGI MGI:102805
eggNOG COG5371
HOGENOM HOG000059572
HOVERGEN HBG018982
InParanoid P55772
KO K01510
PhylomeDB P55772
TreeFam TF332859
ChiTaRS Entpd1
NextBio 281428
PRO PR:P55772
Proteomes UP000000589
Bgee P55772
CleanEx MM_ENTPD1
ExpressionAtlas P55772
Genevestigator P55772
GO GO:0005605
GO:0070062
GO:0016021
GO:0005524
GO:0017110
GO:0017111
GO:0006200
GO:0007186
GO:0030168
GO:0009181
InterPro IPR000407
PANTHER PTHR11782
Pfam PF01150
PROSITE PS01238

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

acts_upstream_of_or_within

GO:2001170

negative regulation of ATP biosynthetic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69265

P

Seeded From UniProt

complete

part_of

GO:0097060

synaptic membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69265

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0051260

protein homooligomerization

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69265

P

Seeded From UniProt

complete

enables

GO:0043262

adenosine-diphosphatase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69265

F

Seeded From UniProt

complete

part_of

GO:0043025

neuronal cell body

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69265

C

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69265

C

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69265

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0033602

negative regulation of dopamine secretion

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69265

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030168

platelet activation

PMID:11929769[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0017111

nucleoside-triphosphatase activity

PMID:11929769[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0017110

nucleoside-diphosphatase activity

PMID:11929769[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0016887

ATPase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69265

F

Seeded From UniProt

complete

part_of

GO:0016323

basolateral plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69265

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69265

C

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69265

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0009181

purine ribonucleoside diphosphate catabolic process

PMID:11929769[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0008021

synaptic vesicle

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69265

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007186

G protein-coupled receptor signaling pathway

PMID:11929769[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:69265

C

Seeded From UniProt

complete

part_of

GO:0005604

basement membrane

PMID:11929769[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000407

F

Seeded From UniProt

complete

enables

GO:0102486

dCTP phosphohydrolase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.6.1.5

F

Seeded From UniProt

complete

enables

GO:0102487

dUTP phosphohydrolase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.6.1.5

F

Seeded From UniProt

complete

enables

GO:0102489

GTP phosphohydrolase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.6.1.5

F

Seeded From UniProt

complete

enables

GO:0102491

dGTP phosphohydrolase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.6.1.5

F

Seeded From UniProt

complete

enables

GO:0102485

dATP phosphohydrolase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.6.1.5

F

Seeded From UniProt

complete

enables

GO:0102488

dTTP phosphohydrolase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.6.1.5

F

Seeded From UniProt

complete

enables

GO:0102490

8-oxo-dGTP phosphohydrolase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.6.1.5

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Sévigny, J et al. (2002) Differential catalytic properties and vascular topography of murine nucleoside triphosphate diphosphohydrolase 1 (NTPDase1) and NTPDase2 have implications for thromboregulation. Blood 99 2801-9 PubMed GONUTS page