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MOUSE:ELN

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Eln
Protein Name(s) Elastin

Tropoelastin

External Links
UniProt P54320
EMBL U08210
AK041860
CH466529
BC051649
CCDS CCDS19725.1
PIR A55721
RefSeq NP_031951.2
UniGene Mm.275320
Mm.404771
ProteinModelPortal P54320
BioGrid 199433
IntAct P54320
STRING 10090.ENSMUSP00000015138
PhosphoSite P54320
MaxQB P54320
PaxDb P54320
PRIDE P54320
Ensembl ENSMUST00000015138
GeneID 13717
KEGG mmu:13717
UCSC uc008zwv.1
CTD 2006
MGI MGI:95317
eggNOG NOG331579
GeneTree ENSGT00730000111510
InParanoid P54320
KO K14211
OMA NGKLPYG
OrthoDB EOG754HSW
Reactome REACT_198996
REACT_198998
REACT_199052
ChiTaRS Eln
NextBio 284500
PRO PR:P54320
Proteomes UP000000589
Bgee P54320
CleanEx MM_ELN
ExpressionAtlas P54320
Genevestigator P54320
GO GO:0071953
GO:0005739
GO:0005578
GO:0050840
GO:0030023
GO:0001974
GO:0030198
GO:0030833
GO:0007519
GO:0043149
InterPro IPR003979
PRINTS PR01500

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0062023

collagen-containing extracellular matrix

PMID:28071719[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(UBERON:0000006)

Seeded From UniProt

complete

enables

GO:0030023

extracellular matrix constituent conferring elasticity

PMID:28071719[1]

ECO:0007666

automatically integrated combinatorial computational and experimental evidence used in manual assertion

F

occurs_in:(UBERON:0000006)

Seeded From UniProt

complete

part_of

GO:0062023

collagen-containing extracellular matrix

PMID:22159717[2]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(UBERON:0002048)|part_of:(UBERON:0001155)

Seeded From UniProt

complete

enables

GO:0030023

extracellular matrix constituent conferring elasticity

PMID:22159717[2]

ECO:0007666

automatically integrated combinatorial computational and experimental evidence used in manual assertion

F

occurs_in:(UBERON:0002048)|occurs_in:(UBERON:0001155)

Seeded From UniProt

complete

part_of

GO:0071953

elastic fiber

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95317
PANTHER:PTN001931357
UniProtKB:P04985
UniProtKB:P15502

C

Seeded From UniProt

complete

part_of

GO:0071953

elastic fiber

PMID:17099216[4]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000057)

Seeded From UniProt

complete

enables

GO:0050840

extracellular matrix binding

PMID:18757743[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0043149

stress fiber assembly

PMID:14614988[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2153007

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030833

regulation of actin filament polymerization

PMID:14614988[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2153007

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030198

extracellular matrix organization

PMID:18757743[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007519

skeletal muscle tissue development

PMID:14614988[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:2153007

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:18614015[7]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0071953

elastic fiber

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P15502
ensembl:ENSP00000351807

C

Seeded From UniProt

complete

involved_in

GO:0003151

outflow tract morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P15502
ensembl:ENSP00000351807

P

Seeded From UniProt

complete

enables

GO:0005201

extracellular matrix structural constituent

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003979

F

Seeded From UniProt

complete

part_of

GO:0062023

collagen-containing extracellular matrix

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003979

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Naba, A et al. (2017) Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. Sci Rep 7 40495 PubMed GONUTS page
  2. 2.0 2.1 Naba, A et al. (2012) The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. Mol. Cell Proteomics 11 M111.014647 PubMed GONUTS page
  3. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  4. Lemaire, R et al. (2007) Microfibril-associated MAGP-2 stimulates elastic fiber assembly. J. Biol. Chem. 282 800-8 PubMed GONUTS page
  5. 5.0 5.1 Manabe, R et al. (2008) Transcriptome-based systematic identification of extracellular matrix proteins. Proc. Natl. Acad. Sci. U.S.A. 105 12849-54 PubMed GONUTS page
  6. 6.0 6.1 6.2 Karnik, SK et al. (2003) Elastin induces myofibrillogenesis via a specific domain, VGVAPG. Matrix Biol. 22 409-25 PubMed GONUTS page
  7. Pagliarini, DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134 112-23 PubMed GONUTS page