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MOUSE:DLGP1
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Dlgap1 (synonyms: Gkap, Kiaa4162) | |
| Protein Name(s) | Disks large-associated protein 1
DAP-1 Guanylate kinase-associated protein PSD-95/SAP90-binding protein 1 SAP90/PSD-95-associated protein 1 SAPAP1 | |
| External Links | ||
| UniProt | Q9D415 | |
| EMBL | AY243846 AK031410 AK033901 AK034182 AK220515 BC062120 BC094369 | |
| CCDS | CCDS28953.1 | |
| RefSeq | NP_081988.3 NP_808307.2 XP_006524236.1 XP_006524239.1 | |
| UniGene | Mm.311840 Mm.367369 | |
| ProteinModelPortal | Q9D415 | |
| SMR | Q9D415 | |
| BioGrid | 230347 | |
| IntAct | Q9D415 | |
| MINT | MINT-136157 | |
| PhosphoSite | Q9D415 | |
| MaxQB | Q9D415 | |
| PaxDb | Q9D415 | |
| PRIDE | Q9D415 | |
| Ensembl | ENSMUST00000060072 ENSMUST00000133983 ENSMUST00000135938 ENSMUST00000155016 | |
| GeneID | 224997 | |
| KEGG | mmu:224997 | |
| UCSC | uc008dky.1 uc008dla.1 uc008dle.2 uc008dlf.2 | |
| CTD | 9229 | |
| MGI | MGI:1346065 | |
| eggNOG | NOG277836 | |
| GeneTree | ENSGT00550000074473 | |
| HOVERGEN | HBG018957 | |
| InParanoid | Q9D415 | |
| KO | K15008 | |
| OMA | AVEVSSC | |
| OrthoDB | EOG75QR37 | |
| TreeFam | TF321382 | |
| ChiTaRS | Dlgap1 | |
| NextBio | 377488 | |
| PRO | PR:Q9D415 | |
| Proteomes | UP000000589 | |
| Bgee | Q9D415 | |
| ExpressionAtlas | Q9D415 | |
| Genevestigator | Q9D415 | |
| GO | GO:0030054 GO:0097481 GO:0045211 GO:0045202 GO:0007268 | |
| InterPro | IPR005026 | |
| Pfam | PF03359 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0014069 |
postsynaptic density |
ECO:0000315 |
C |
Figure 6A and C, A decrease of PSD proteins in postsynaptic density fraction. There was a decrease in GKAP protein in mutant Shank3 mice. |
complete | |||||
|
enables |
GO:0044877 |
protein-containing complex binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0099092 |
postsynaptic density, intracellular component |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620223 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620223 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0098919 |
structural constituent of postsynaptic density |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620223 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0070842 |
aggresome assembly |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620223 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0061136 |
regulation of proteasomal protein catabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620223 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0045211 |
postsynaptic membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620223 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0045202 |
synapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045202 |
synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620223 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0044877 |
protein-containing complex binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620223 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0035418 |
protein localization to synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620223 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0019904 |
protein domain specific binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620223 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620223 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0099562 |
maintenance of postsynaptic density structure |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0098919 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007268 |
chemical synaptic transmission |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0023052 |
signaling |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045202 |
synapse |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0007268 |
chemical synaptic transmission |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045211 |
postsynaptic membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045202 |
synapse |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030054 |
cell junction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Wang, X et al. (2011) Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3. Hum. Mol. Genet. 20 3093-108 PubMed GONUTS page
- ↑ Welch, JM et al. (2004) Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse. J. Comp. Neurol. 472 24-39 PubMed GONUTS page
- ↑ Munton, RP et al. (2007) Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol. Cell Proteomics 6 283-93 PubMed GONUTS page
- ↑ Serpinskaya, AS et al. (1999) Synapse formation by hippocampal neurons from agrin-deficient mice. Dev. Biol. 205 65-78 PubMed GONUTS page
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