MOUSE:CXCR5

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Cxcr5 (synonyms: Blr1, Gpcr6)
Protein Name(s)	C-X-C chemokine receptor type 5 CXC-R5 CXCR-5 Burkitt lymphoma receptor 1 homolog
External Links
UniProt	Q04683
EMBL	X71788 AK155954 AK156087 AK157016 CH466522 BC064059 L20332
CCDS	CCDS23115.1
PIR	S42628
RefSeq	NP_031577.2
UniGene	Mm.491799 Mm.6246
ProteinModelPortal	Q04683
SMR	Q04683
DIP	DIP-5919N
IntAct	Q04683
MINT	MINT-1672594
GuidetoPHARMACOLOGY	72
PhosphoSite	Q04683
PRIDE	Q04683
Ensembl	ENSMUST00000062215 ENSMUST00000179828
GeneID	12145
KEGG	mmu:12145
UCSC	uc009pdx.1
CTD	643
MGI	MGI:103567
eggNOG	NOG146951
GeneTree	ENSGT00760000118785
HOGENOM	HOG000234122
HOVERGEN	HBG106917
InParanoid	Q04683
KO	K04190
OMA	GLAHCCL
OrthoDB	EOG7R8322
TreeFam	TF330966
Reactome	REACT_230248 REACT_250376
NextBio	280479
PRO	PR:Q04683
Proteomes	UP000000589
Bgee	Q04683
CleanEx	MM_CXCR5
Genevestigator	Q04683
GO	GO:0009897 GO:0016021 GO:0016494 GO:0042113 GO:0006935 GO:0006955 GO:0048535 GO:0032467
InterPro	IPR001053 IPR000355 IPR000276 IPR017452
PANTHER	PTHR24227 PTHR24227:SF33
Pfam	PF00001
PRINTS	PR00564 PR00237
PROSITE	PS00237 PS50262

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0060326	cell chemotaxis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001200797 UniProtKB:P51684	P		Seeded From UniProt	complete
enables	GO:0019957	C-C chemokine binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:104616 MGI:MGI:107182 MGI:MGI:1333797 MGI:MGI:1891697 PANTHER:PTN001200797 RGD:708446 UniProtKB:P32246 UniProtKB:P51677 UniProtKB:P51681 UniProtKB:P51684 UniProtKB:P61073	F		Seeded From UniProt	complete
enables	GO:0019956	chemokine binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001200797 UniProtKB:P49682 ZFIN:ZDB-GENE-031116-61	F		Seeded From UniProt	complete
involved_in	GO:0019722	calcium-mediated signaling	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001200797 RGD:621528 UniProtKB:P51681 UniProtKB:P51684 UniProtKB:P61073	P		Seeded From UniProt	complete
enables	GO:0016493	C-C chemokine receptor activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103011 MGI:MGI:104616 MGI:MGI:104618 MGI:MGI:106185 MGI:MGI:107182 MGI:MGI:107824 MGI:MGI:1096320 MGI:MGI:1201402 MGI:MGI:1333797 MGI:MGI:1341902 MGI:MGI:1891697 PANTHER:PTN001200797 UniProtKB:P32246 UniProtKB:P51681 UniProtKB:P51684	F		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103011 MGI:MGI:103567 MGI:MGI:106185 MGI:MGI:107182 MGI:MGI:107824 MGI:MGI:109563 MGI:MGI:1277207 MGI:MGI:1333797 PANTHER:PTN001200797 RGD:621528 RGD:708446 UniProtKB:P32246 UniProtKB:P51681	C		Seeded From UniProt	complete
involved_in	GO:0007204	positive regulation of cytosolic calcium ion concentration	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1096320 PANTHER:PTN001200797 RGD:1308562 RGD:2906 RGD:620596 RGD:621528 UniProtKB:P32246	P		Seeded From UniProt	complete
involved_in	GO:0006955	immune response	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103011 MGI:MGI:106185 PANTHER:PTN001628461 UniProtKB:P32246	P		Seeded From UniProt	complete
involved_in	GO:0006935	chemotaxis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103011 MGI:MGI:104616 MGI:MGI:107824 MGI:MGI:1096320 MGI:MGI:1201402 MGI:MGI:1333797 MGI:MGI:1341902 MGI:MGI:1346338 PANTHER:PTN001200797 UniProtKB:F1R6D3 UniProtKB:P25025 UniProtKB:P51684 ZFIN:ZDB-GENE-031116-61	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048535	lymph node development	PMID:12732660^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2158677	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032467	positive regulation of cytokinesis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P32302	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030595	leukocyte chemotaxis	PMID:25348153^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:23583643^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000084)	Seeded From UniProt	complete
involved_in	GO:0070098	chemokine-mediated signaling pathway	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0016494	P		Seeded From UniProt	complete
involved_in	GO:0070098	chemokine-mediated signaling pathway	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0016493	P		Seeded From UniProt	complete
involved_in	GO:0032467	positive regulation of cytokinesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P32302 ensembl:ENSP00000292174	P		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276	F		Seeded From UniProt	complete
involved_in	GO:0006935	chemotaxis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001053	P		Seeded From UniProt	complete
involved_in	GO:0006955	immune response	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001053	P		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276 InterPro:IPR001053	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276 InterPro:IPR001053 InterPro:IPR017452	C		Seeded From UniProt	complete
enables	GO:0016494	C-X-C chemokine receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001053	F		Seeded From UniProt	complete
involved_in	GO:0042113	B cell activation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001053	P		Seeded From UniProt	complete
involved_in	GO:0048535	lymph node development	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001053	P		Seeded From UniProt	complete
involved_in	GO:0042113	B cell activation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0075	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0297	F		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0297	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0807	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Luther, SA et al. (2003) Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7 ligands in lymph node development. J. Exp. Med. 197 1191-8 PubMed GONUTS page
↑ Wang, X et al. (2014) GPR18 is required for a normal CD8αα intestinal intraepithelial lymphocyte compartment. J. Exp. Med. 211 2351-9 PubMed GONUTS page
↑ Vogel, KU et al. (2013) Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation. Immunity 38 655-68 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:12732660-2] Luther, SA et al. (2003) Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7 ligands in lymph node development. J. Exp. Med. 197 1191-8 PubMed GONUTS page

[PMID:25348153-3] Wang, X et al. (2014) GPR18 is required for a normal CD8αα intestinal intraepithelial lymphocyte compartment. J. Exp. Med. 211 2351-9 PubMed GONUTS page

[PMID:23583643-4] Vogel, KU et al. (2013) Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation. Immunity 38 655-68 PubMed GONUTS page

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MOUSE:CXCR5

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Annotations

Notes

References

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